Search PubMed⌕ Search

Biomedical subjects

M Virolainen

Publications and source records attributed to M Virolainen.

At least 55 records · Page 3Linked to original sources

Fractionation studies on human leucocyte dialyzates. Demonstration of three components with transfer factor activity.

Fractionation of dialyzates of human leucocyte lysates on a Sephadex G-10 column yielded seven fractions. Oidiomycin sensitivity could be induced with fractions I, III and VI in those recipients whose skin tests had previously been negative. Uraemic patients, who were skin test negative to 100 TU of PPD, regained their in vivo reactivity to PPD after receiving 5 mug of fraction VI, while no alteration in their blast transformation responses to the antigen was observed. We suggest that the active components at least in fractions III and VI, and perhaps also in fraction I, act nonspecifically by stimulating weak immune reactivity or by supporting reactions leading to the expression of this reactivity.

Adult↗

Roentgenographic findings of the lumbosacral spine in preemployment examinations of lumbermen with special reference to spondylolisthesis.

The X-ray findings of the lumbar spine in the preemployment examination of 807 lumbermen are presented. From the applicants 11.4% were rejected because of roentgenological and/or clinical low back abnormalities. The youngest age group showed a high frequency of spondylolisthesis (8%). The possible role of heavy work in adolescence in the etiology of spondylolisthesis is discussed.

Adolescent↗