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Biomedical subjects

M Vadrot

Publications and source records attributed to M Vadrot.

4 recordsLinked to original sources

[Cesium].

Cesium is an alkaline metal close to Rubidium, which is studied in psychopharmacology in the prospect of a possible antidepressive effect. It has stimulating properties of the motor activity on the animal, antagonizes some sedative substances but does not modify either self-stimulation behaviour or induced agressivity. Given in large doses, Cesium presents hypertensive effects bound with a stimulation of the adrenal Epinephrine secretion. As for the synapses Cesium increases the neuro-transmitter release. However the Norepinephrine turn-over is not modified in the central nervous system while that of Serotonin is increased as well as the cerebral concentrations of Tryptophan, Serotonin and 5.HIAA. These very fragmentary data about the toxico-pharmacological properties of Cesium, as well as the very prolonged half-life of this ion (from 50 to 100 days), explain that contrary to Rubidium it has not still been used in man.

Animals

[Ultrasonography of the pancreas. Diagnostic problems and findings in cases of solid pancreatic masses (author's transl)].

By using rigourous examination techniques and interpretive criteria, ultrasonography of the pancreas can, in many cases, confirm the etiological diagnosis of solid pancreatic masses. Factors influencing diagnosis are the volume and shape of the pancreas, the ultrasound structure, the attenuation of ultrasounds, the outline of the pancreas, and the effect on neighbouring structures. The association of signs is often characteristic and can differentiate benign from malignant masses.

Acute Disease

[Echotomography in the study of abdominal lymphadenopathies. Technique of examination and typical appearances (author's transl)].

Lymphographic opacification of the abdominal nodes is only partial, and it is therefore useful to have available another examination for the diagnosis of lymphadenopathies. Echography would seem to merit an important role since out of a series of 100 patients, it led to a positive and confirmed diagnosis in 78% of cases with 22% of errors, including 4% of false positives. In almost 20% of cases, echography gave additional information to that of lymphography, this justifying the simultaneous application of both examinations, either diagnostically or in the context of the surveillance of treatment. Lymphadenopathies are regularly visible from a diameter of 3 cm upwards, their structure is generally very slightly echogenic only and they may be perfectly precisely located. Problems of differential diagnosis are minimal if the technique is applied carefully, by contrast the appearance of lymphadenopathies is very similar and offers no indication as to the aetiology.

Abdomen