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Biomedical subjects

M V Makhnev

Publications and source records attributed to M V Makhnev.

8 recordsLinked to original sources
PubMed1996

[Respiratory system involvement in pseudotuberculosis].

Clinical, microbiological, x-ray and immunological examinations of 1376 patients with pseudotuberculosis and 465 patients with acute respiratory diseases of viral or coccal origin, the trends in annual morbidity for the above diseases followed up within 7 years in the populations where the patients were registered and experimental investigations on rabbits provided evidence for primarily generalized pattern of pseudotuberculosis infection and a direct relationship between pulmonary lesions in the animals and effective dose of the infectant, route of the infection. The patients had nonspecific (non-yersiniosis) lesions of the respiratory system. Frequency of the infection was greater in cold seasons, especially in those who did not complete social and biological adaptation to new conditions, and depended on seasonal fluctuations of respiratory infection morbidity in nonrandom populations.

Acute Disease↗
PubMed1994

[The nature, frequency, specificity and duration of the retention of changes in different parts of the gastrointestinal tract in yersiniosis].

400 patients with yersiniosis, shigellosis, salmonellosis and abdominal typhoid were examined clinically, roentgenologically and using various instrument techniques for changes in the stomach and intestine. Yersiniosis and abdominal typhoid were characterized by dyskinesia of the small intestine and ileotyphlitis, Flexner's shigellosis by catarrhal-hemorrhagic proctosigmoiditis, Sonne salmonellosis and shigellosis by enteritis. Terminal ileitis occurred more frequently in yersiniosis patients in recurrence. After yersiniosis the patients may retain (for 3-24 months) lesions of ileocecal intestine without or rare clinical symptoms and develop chronic disease similar to initial stage of Crohn' disease.

Acute Disease↗
PubMed1994

[Operator function study by using a multipurpose digital test].

The article describes the new psychophysiological test, as well as the evaluation formulas and application methods. This test makes it possible to obtain information in the conditions of long cruise about the performance capabilities of seamen who went through infectious diseases in order to study their readaptation and rehabilitation process. Traditional tests of Landolt's rings or Anfimov's letters don't dispose these possibilities. The new test provide information not only about visual analyser, but also concerning different psychophysiological characteristics of a patient.

Communicable Diseases↗
PubMed1993

[The functional status and work capacity of convalescents after pseudotuberculosis].

The authors have studied the recovery process of functional state and performance capability in 887 convalescents after pseudotuberculosis. All the examinees were servicemen of male sex, age 18-23, without somatic or psychoneurological disorders. Clinical, biochemical, immunological and psychophysiological methods of examinations were applied. It was found out that the outcomes of the diseases were favourable. At the same time in 79.8% of patients functional disorders of nerve, cardiovascular, hepatobiliary and digestive systems were taking place for one month. A half of convalescents had a low performance capability and low psychoemotional labour motivation. Application of adaptogens, physiotherapy, and a system of gradually growing physical loads which was elaborated by the authors give the possibility to improve and shorten the period of rehabilitation.

Adolescent↗
PubMed1990

[The basic features of the pathogenesis of pseudotuberculosis (yersiniosis)].

A new pathogenetic pattern of pseudotuberculosis has been derived on the basis of original clinical, anatomical and experimental findings as well as literature data. Careful consideration is given to: a basic mode of infection (alimentary), emergence of the primary affection with a rapid blood invasion by the agent (primary bacteremia), development of specific sensitization, multiorgan secondary focal impairment with lymphogenic dissemination of the infective agent (specific pseudotuberculous polyadenitis), formation of secondary immunodeficiency, consequent repeat bacteremias, recurrences, symptoms of infectious process aggravations, immunological rearrangement with dominating delayed hypersensitivity. As a rule, the disease terminated by elimination of the secondary foci and recovery.

Humans↗