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Biomedical subjects

M V Khomenko

Publications and source records attributed to M V Khomenko.

29 records · Page 2Linked to original sources

[Ten-year experience of the postgraduate education for general practitioners].

The article summarizes a 10-year experience of teaching general practitioners in internship. Different kind of teaching in the 1-year term was described as well as given questionnaire design results of internists to be. Intership organization development was considered in the article, it will help the work of general practitioners to be more effective.

Education, Medical, Graduate↗

[Chondrocalcinosis in gout].

Problems of pathogenesis, diagnosis and therapy of gout and chondrocalcinosis in which deposits of uric acid salts and calcium are found in the articular tissue are of primary importance in modern rheumatology. The authors give observations of 10 out of 218 patients with primary gout in whom roentgenology had revealed signs of calcium salt deposits in the joints and periarticular tissue.

Adult↗

[The characteristics of the urinary syndrome in patients with chronic glomerulonephritis].

Quantitative measures of proteinuria, hematuria, lipoiduria and cylindruria have been studied in 156 patients with chronic glomerulonephritis in the course of long-term survey. The parameters evaluated and their combinations were noted to vary considerably. Proteinuria and/or hematuria not infrequently associated with cylindruria and/or lipoiduria were common in mesangioproliferative, mesangiocapillary and membranous glomerulonephritis. Patients with focal-segmentary glomerulosclerosis-hyalinosis and minimal glomerulonephritis in the stage of remission revealed no pathological changes in urine. Statistically valid correlation was established between the degrees of proteinuria (as well as between those of lipoiduria) and proteinuria while there was no link between proteinuria and hematuria.

Adolescent↗

[The clinico-morphological characteristics of glomerulonephritis in infectious endocarditis].

Clinicomorphological characteristics of glomerulonephritis in infectious endocarditis (IEGN) were studied in 62 patients (with samples of autopsy material being used in 52 instances). IEGN presents with dissaminated and focal proliferative alterations involving extracapillary and/or tubulointerstitial components, and is characterized by a broad variability of indices for proteinuria, hematuria and cylindruria. In diffuse prolipherative glomerulonephritis the degree of proteinuria and cylindruria appear to be significantly higher than in focal segmental proliferative glomerulonephritis, as is the incidence rate of development of renal insufficiency and its gravity.

Adolescent↗

[The clinico-morphological characteristics and treatment of minimal-change glomerulonephritis and focal-segmental glomerulosclerosis-hyalinosis].

Clinical and morphological features were analysed of the morbid condition in 46 patients with glomerulonephritis presenting with minimal alterations (GNMA) and 12 those with focal-and-segmental glomerulosclerosis-hyalinosis (FSGH), of whom there were twenty nine males and twenty nine females ranging between 15 to 54 years. In all cases morphologic diagnosis was established on the basis of vital histologic investigation of renal tissue. Immediate results were assessed of glucocorticoid and cytostatic therapy instituted at different stages of the condition. High effectiveness was documented of glucocorticosteroids in GNMA patients along with the ability of cyclophosphamide to significantly decrease the frequency of exacerbations and make such patients free from steroid dependency. GSGH patients derived no benefit from glucocorticoids while cyclophosphamide was associated with complete GH patients azathioprine therapy had no positive effect on the course of the illness.

Adolescent↗