[Possible mechanisms of the occurrence of new loci of defective endogenous proviruses].
Explore the source record for details and available documents.
Biomedical subjects
Publications and source records attributed to M V Chernov.
Explore the source record for details and available documents.
The composition and structure of endogenous proviruses present in the genome of Italian Partridge chickens were studied by the method of blot hybridization using RAV-2 [32P]DNA or LTR of RSV as hybridization probes. The genomes of 5 out of 39 chickens analyzed did not contain endogenous proviruses related to RAV-2. Different sets of five so far undescribed endogenous proviruses, differing in the structure and location, were detected in the DNA of other IP chickens. None of them is identical in its structure to the DNA of the endogenous chicken virus RAV-0, all five loci of endogenous proviruses of IP chickens were defective. The origin, the patterns of genetic variation and the function of endogenous proviruses are discussed.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
The composition and structure of endogenous proviruses in the genome of Italian partridge chicken was studied by the blot-hybridization method using 32P-DNA of RAV-2 virus as a probe. Among 34 fowls examined, 5-contained no endogenous proviruses related to fowl leukemia viruses. DNA of the other fowls contained various combinations of 4 previously undescribed endogenous proviruses varying in structure and localization. None of them was identical in its structure with DNA of endogenous fowl virus RAV-0, all the four discovered loci have deletions. The origin, modes of genetic variability, and function of endogenous proviruses are discussed.