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Biomedical subjects

M Uono

Publications and source records attributed to M Uono.

At least 37 records · Page 2Linked to original sources
PubMed1981

Clioquinol intoxication occurring in the treatment of acrodermatitis enteropathica with reference to SMON outside of Japan.

Many past cases of SMON have occurred in Japan but since 1975 no new cases have been reported. One type of SMON is associated with acrodermatitis enteropathica which has a very high frequency of occurrence in association with administration of clioquinol. Acrodermatitis enteropathica with SMON almost always has a high occurrence of visual impairment, but other sensory disturbances are slight or absent, while common adult SMON is just the opposite. We do not know why these differences occur.

Acrodermatitis↗
PubMed1980

A case of facial diplegi following herpes zoster ophthalmicus.

A 71-year-old man developed a facial diplegia following right ophthalmic zoster. Neurological examination also revealed loss of reflexes in the lower limbs with increase of CSF protein. Unusual cases of the Ramsay Hunt syndrome and Guillain-Barré syndrome seen with herpes zoster were reviewed. These cases including our case may suggest that the bilateral involvement or its wider spread throughtout nervous tissue can rarely occur in the Ramsay Hunt syndrome and its subgroups.

Aged↗
PubMed1977

beta-Galactosidase deficiency in juvenile and adult patients. Report of six Japanese cases and review of literature.

Six juvenile and adult patients with progressive neurological diseases and beta-galactosidase deficiency were reported. Any diseases known to date were denied. These cases together with ten case reports in the literature were reviewed and were classified into three groups from clinical and biochemical points. Group 1 patients were characterized by progressive ataxia and myoclonus with gargoyl changes and macular cherry-red spots. In this syndrome beta-galactosidase activity seems to be secondarily affected by other biochemical defects. A group 2 patient showed similar neurological manifestations without gargoyle changes or macular cherry-red spots. Patients with these clinical features not associated with beta-galactosidase deficiency have also been described in the literature. Group 3 patients had progressive pyramidal and extrapyramidal disease without gargoyl changes or macular cherry-red spots. These cases may represent juvenile and adult type GM1-gangliosidosis. Accumulation of GM1 has not yet been demonstrated.

Adolescent↗