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Biomedical subjects

M Uhari

Publications and source records attributed to M Uhari.

200 records · Page 12Linked to original sources

Social activities in the families of children with acute lymphoblastic leukemia.

The social activities of 15 children with acute lymphoblastic leukemia (ALL) and their families (index families) were compared during chemotherapy with those of control families matched for the numbers, ages, and sex of the children. Data concerning the day care arrangements for the children of all the index and control families were obtained by a questionnaire. The children under school age in the index families were more frequently cared for at home or in a family than were those in the control families (14/14 vs 13/26, P < 0.01). All visits made, visitors received, and gatherings of 12 index and 12 control families were recorded by means of diaries during two 4-week periods in May and September 1989. The adults and children in the ALL families made an average of 5.5 and 3.4 visits per person, respectively, during each 4-week period, with the corresponding figures for the control families being 5.4 and 4.4. The mean number of adult and child guests in the index and the control families and the corresponding figures for visits were similar. The mean numbers of adults and children present at places visited by an index and control family did not differ statistically significantly, and the mean number of gatherings attended per adult and child during a period of 4 weeks was also similar in both groups of families. The differences were found in day care arrangements, but social activities as recorded by visits and gatherings were similar in the families of the children with ALL and the controls.

Adolescent↗

Persistence of collateral circulation after correction of aortic coarctation.

The persistence of collateral circulation was evaluated one year after the correction of experimental aortic coarctation (CoA) by assessing renal perfusion with the Xenon 133-washout method and measuring distal aortic blood pressure during cross-clamping of the thoracic aorta. CoA was created in 7 puppies at 2 months of age and was corrected after a follow-up with a venous patch when the dogs were 9 months old. Two of the dogs were lost during the corrective operation due to anaesthetic complications. Four sham-operated dogs served as controls. One year after correction of CoA, four of the dogs had a pressure gradient of less than 5 mmHg at the site of CoA and one a pressure gradient of 15 mmHg. In renal perfusion measurements a mean decrease of 49% and 96% was found in the study and control groups, respectively. Blood pressures in the distal aorta decreased 47% and 83%, respectively. Two dogs in the study group had a distal blood pressure under 50 mmHg and their renal perfusion decreased markedly. Collateral circulation decreased with time after a good anatomic correction of CoA, so that one year after correction of experimental CoA about one half of the initial collateral capacity remained. This suggests that in most reoperations performed at least one year after the primary corrections, temporal shunting or a left side bypass is necessary to ensure sufficient circulation in the distal organs.

Animals↗