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Biomedical subjects

M Ueda

Publications and source records attributed to M Ueda.

At least 1,513 records · Page 84Linked to original sources
PubMed1976

Post-traumatic anterior pituitary insufficiency developed in a patient with partial lipodystrophy.

A case of partial lipodystrophy developing anterior pituitary insufficiency, chronic glomerulonephritis and pulmonary fibrosis was reported. The patient died of respiratory failure secondary to pituitary crisis during the hospital course. From the clinical course in recent several years and the postmortem examination the head injury following car accident in the past history was considered to be the most plausible cause of hypopituitarism. The etiology of pulmonary fibrosis remained unresolved.

Adrenal Glands↗
PubMed1976

A successful method for development of voluntary alcohol intoxication in mice.

Eight strains of male mice, C57BL, C3H SWM, SW, KK, KSB, KR and DBA, were fed on a standard pelletized diet and offered a choice of water or 10% sake solution (sake containing 10% alcohol). Both young (3 months of age) and old (8 months of age) groups were studied simultaneously. The degree of intoxication was measured by recording the drinking behavior on a pulse recorder, by calculating gaschromatographically the blood alcohol concentration, by taking depth electroencephalogram readings and so on. Intoxication, shown by lack of coordination such as grossly impaired gait, was observed only in the older mice of strain with a moderate natural alcohol preference such as C3H, SWM, SW, KK and KSB. In general, the intoxicated mice were over 9 months of age, tended to consume fluids regardless of the time of day or night and suffered a loss of body weight. The blood alcohol levels of them were over 4.6%. The threshold elevation of the ascending reticular activating system on electroencephalogram in a intoxicated mouse reached about 167%. The present study provides a successful method for the development of voluntary alcohol intoxication in mice.

Age Factors↗
PubMed1975

Hexokinase isozyme pattern in CCl(4)-injured rat liver.

Activities of hexokinase isozymes in carbon tetrachloride (CCl(4))-injured rat liver were determined quantitatively by DEAE-cellulose column chromatography and compared with those of regenerating liver, fetal liver and ascites hepatoma cells (AH 130). The CCl(4)-injured liver revealed an isozyme distribution with predominant Types I, II and III (3.2, 8.8 and 6.8 times higher than the control values, respectively) and with undetectable activity of Type IV hexokinase (glucokinase). Although the isozyme pattern generally resembled that of fetal liver or hepatoma cells, the relatively high activity of hexokinase Type III in CCl(4) treatment characterizes the pattern of hexokinase isozyme in acue liver damage.

Animals↗
PubMed1975

Periodicity of recurrence of 'phasic type' of schizophrenia.

Seventy-nine "phasic type" of schizophrenics (38 males, 41 females), who in their progress of schizophrenia had a certain dilapidation of personality, were observed and treated for more than four years and were investigated as to the intervals of their recurrences. The recurrence totaled 198. It was characteristic of periodic occurences that 61.1% of them occurred within an interval of eight to eleven months (about 240-330 days) and 10.6% of them occurred within an interval of approximate multiples of eight to eleven months (as measured from the start of one recurrence period to the start of the next). The interval between recurrences was not markedly affected by seasonal changes, which raised or lowered the temperature and lengthened or shortened the day. Nor was it affected by tranquilizers, such as phenothiazine-derivatives, butyrophenone-derivatives, or by the psychogenic moment (though the picture of recurrences might be affected by all of these). The rhythm of recurrences of the "phasic type" of schizophrenia seems to be endogenous in free-running nature, as if schizophrenics live in an empty world.

Adult↗