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M Uechi

Publications and source records attributed to M Uechi.

41 records · Page 3Linked to original sources
PubMedDate not supplied

Morphological characterization of ductular reactions in canine liver disease.

Intrahepatic bile duct proliferation (ductular reaction) was examined histologically, immunohistochemically and ultrastructurally in four cases of canine liver disease, diagnosed as chronic hepatitis, liver fibrosis, cirrhosis and cholangiocellular carcinoma. Ductular reaction was a common finding in all cases. Most of the proliferated bile ducts were similar to normal bile ducts. In addition, duct-like structures occurred, consisting of hepatocytes and of intermediate cells that had phenotypic characteristics of both cholangiocytes and hepatocytes. The proliferated bile ducts were immunohistochemically negative for proliferating cell nuclear antigen (PCNA) and stem cell factor (SCF). The proliferated bile ducts in these four cases of canine liver disease thus showed both typical ductular reactions, such as elongation and tortuosity of the existing bile ducts, and atypical ductular reactions resulting from metaplasia of hepatocytes.

Animals↗
PubMedDate not supplied

The variation in excretory urinary glycyl-prolyl dipeptidyl aminopeptidase in dogs.

We studied the excretory variation of urinary glycyl-prolyl dipeptidyl aminopeptidase (GP-DAP, EC 3.4.14.5) in dogs. Adult domestic mongrel dogs (seven males and nine females, 7.5 to 13 kg bodyweight) which were considered to be healthy by laboratory tests were used. Urine and blood samples were obtained every four hours. Urine volume was measured for each sample and urine GP-DAP activity, and creatinine levels were determined. Creatinine clearance, creatinine excretion, GP-DAP activity and GP-DAP index (GP-DAP/Cr ratio) did not show any significant variation between the time periods. However, urine volume and urinary GP-DAP excretion significantly increased from 8:00 am to 12:00 pm. The GP-DAP index in spot urine samples showed low correlation with 24 hour GP-DAP excretion. In addition, a sex difference was observed in GP-DAP excretion. In conclusion, urinary GP-DAP excretion showed a circadian variation and sex difference. Therefore, GP-DAP in spot urine is not of use for the detection of renal disorders, and the 24-hour excretion value of GP-DAP should be determined.

Aminopeptidases↗
PubMedDate not supplied

[A study of the path diagram of the relationship between life style, mental health and psychosocial factors of nurses working at hospitals in Japan].

We conducted a study of 1,143 nurses working at hospitals in the southern part of Ibaraki prefecture in Japan to clarify the path diagram of the relationship between life style, mental health and psychosocial factors. General health questionnaire, life practice index, social support, number of night shifts and perceived health-status were used in this study. The data were analyzed using multivariate analysis and path analysis. The results are as follows: 1) The path analysis showed that General health questionnaire was directly affected by perceived health-status and social support. 2) General health questionnaire was directly and indirectly affected by Life practice index and social support. 3) Social support and number of night shifts were indirectly affected the General health questionnaire through the perceived health-status.

Health Status↗