Search PubMed⌕ Search

Biomedical subjects

M Trillet

Publications and source records attributed to M Trillet.

115 records · Page 7Linked to original sources
PubMedDate not supplied

[Bucco-linquo-facial and choriform hyperkinesies (author's transl)].

These bucco-linguo-facial and choriform hyperkinesies still remain all too frequent in many neurological diseases. The authors study exclusively the dyskinesies of essential origin or iatrogenous including the post neuroleptic and post dopatherapy dyskinesies. All the neuroleptics can be involved at different stages of the treatment, giving rise to difficulties in the diagnosis. Dopatherapy in the Parkinson disease is also responsable of many dyskinesias. Time of appearance after the drug's taking, significance and treatment are discussed. The idiopathic dyskinesis are more unusual either with the some only facial involvement, or in association with another abnormal movements. The physiopathology is doubtful, so the treatment is often very difficult.

Antipsychotic Agents↗
PubMedDate not supplied

[Hemiballismus with logorrhea and thymo-affective disinhibition caused by hematoma of the left subthalamic nucleus].

A 71 year-old hypertensive right-handed man presented a small intracerebral haematoma limited to the left subthalamic nucleus that resulted in right hemiballismus and a neurobehavioral disinhibition syndrome. The latter associated logorrhoea and euphoria, but there was no frontal signs nor mental confusion. The patient kept full insight into his mental change, that contrasted with his prior personality. Hemiballismus and the manic-like state resolved within 2 months. This case and some others from the literature illustrated that a focal lesion in the basal ganglia could result in manic-like affective change, and that a relation did exist between hyperkinetic syndrome and euphoria. Our case contrasted with most of the published cases of neurobevioral changes following basal ganglia discrete lesions, expressing as hypokinesia, apathy and loss of motivation. With reference to the functional circuits linking the frontal cortex and the basal ganglia, as described by Alexander, this syndrome of combined disinhibition of motricity, speech and affect could involve either the lateral orbito-frontal or the anterior cingulate loops, more especially the indirect pathways travelling through the subthalamic nucleus, lesion of which is known to disinhibit thalamo-cortical activity.

Aged↗
PubMedDate not supplied

[Non-syringomelic medullary syndrome with Arnold-Chiari malformation (author's transl)].

The authors present 15 observations of a medullary syndrome of the non-syringomelic type, in patients with Arnold-Chiari's malformation (type I; 13 times - type II; twice), verified surgically, and without severe malformations of the occipito-vertebral articulation. Brown-Sequard's disease was present in 6 cases, subacute combined degeneration in 2 cases, and pyramidal lesions were very predominant in two other cases. The last 5 cases had cordonal signs associated with signs of disturbance of the anterior horns in the medulla, affecting all four limbs, and more especially the lower limbs. In four cases the medullary cavity was exposed, and in two cases extended along the whole length of the cord up to the terminal cone. The literature is reviewed and diagnostic and pathogenic problems raised by these myelopathies are discussed. They merit systematic investigation.

Arnold-Chiari Malformation↗