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Biomedical subjects

M Trauner

Publications and source records attributed to M Trauner.

64 records · Page 4Linked to original sources
PubMed1982

[Experiences and results in the treatment of scaphoid fractures and pseudarthroses of the hand with special reference Matti-Russe osteoplasty].

The author deals with the specific problems involved in the diagnosis of scaphoid fractures and the mechanical causes responsible for non-union of the scaphoid bone because of movements of the hand joint and blood supply of the scaphoid bone. Reference is made to details of surgery according to Matti and Matti-Russe which the author considers to be particularly important while assuming that the reader is already familiar with the technique. Emphasis is also placed on the importance of sufficiently long and careful immobilisation and subsequent physiotherapy. Alternative methods of surgery in special cases and advanced non-unions or arthroses of the hand joint are indicated and the results of treatment conducted by the author during the period 1. 1. 1967 to 31. 12. 1979 are tabulated.

Bone Screws↗
PubMed1980

[Restoration after burns of the back of the hand].

In burn injuries due to their exposed situation the hands are frequently injured and in the moment of the accident they are often used as a shield in front of the face. Mainly the back of the hands are involved. In reconstruction after burns of the back of the hands the scared skin is excised under tourniquet, the displaced interdigital webs are corrected by the method of Tanzer and the skin defect is covered by a thick split-skingraft. From case to case additional operations are: replacement of lost extensor tendons, capsulotomies of the MP-joints, arthrodeses of destroid fingerjoints and amputation of fingers which can't be reconstructed.

Arthroplasty↗
PubMedDate not supplied

Complications and surgical interventions during 4 years of biliary extracorporeal shockwave lithotripsy.

BACKGROUND/AIMS: Extracorporeal shockwave lithotripsy (ESWL) of renal concrements, a revolutionary therapeutic concept, was introduced into clinical routine in the early 1980s. In this study, complications and surgical interventions of biliary extracorporeal shockwave lithotripsy were investigated. MATERIAL AND METHODS: Two hundred-eighty patients with gallbladder stones underwent extracorporeal shockwave lithotripsy during a 4 year (January 1990-December 1993) investigation period. Two hundred four patients were female, and 76 patients were male with a mean age of 48 years. All patients were symptomatic. Selection was carried out following the "Munich criteria" and the selection rate was 15.3% of all referred patients (n = 1831). One hundred eighty-eight patients had solitary stones, 92 patients presented with multiple stones (maximum 3 stones), with an average of 1.7 stones and a mean stone volume of 2.4 cm3 and stone diameter of 16.5 mm. Shockwave lithotripsy was performed with a second generation electrohydraulic lithotriptor with a mean of 2.1 sessions. Mean duration of one session was 50 min, 1331 discharges were applied on average with a mean power of 22.7 kV. RESULTS: Analgesia, with Alfetanil (mean 2.3 mg), was necessary in 68% of all treatment sessions. Fragmentation could be achieved in 81% of the cases, stone clearance was observed in 172 cases (66.4%) out of 258 patients after 12 months. Twenty-two patients were treated in 1993 and are still under observance. Side effects such as colic after treatment were observed in 88 cases (31.4%). In seven cases, severe complications such as impaction of fragments in the papilla of Vater followed by serochemical pancreatitis were seen. An urgent endoscopic sphincterotomy was necessary in these 7 cases (2.5%). Within 4 weeks after shockwave treatment in 4 cases 1.4% emergency cholecystenomy had to be performed. Elective cholecystectomy was done in 16 patients (5.7%). There were no deaths observed during the investigation period. CONCLUSION: Based on the results of our series, we do not recommend biliary ESWL in patients with stone volumes exceeding 14 cm3 (3cm), the high fragment volume after sufficient fragmentation by shockwaves indicates long term oral dissolution therapy. The probability of complications will be increased by the presence of larger fragments.

Adult↗
PubMedDate not supplied

Molecular alterations of canalicular transport systems in experimental models of cholestasis: possible functional correlations.

The discovery of unidirectional, ATP-dependent canalicular transport systems (also termed "export pumps") for bile salts, amphiphilic anionic conjugates, lipophilic cations, and phospholipids has opened new opportunities for understanding biliary physiology and the pathophysiology of cholestasis. In addition, ATP-independent canalicular transport systems for glutathione and bicarbonate contribute to (bile acid-independent) bile formation. Canalicular excretion of bile salts and several non-bile acid organic anions is impaired in various experimental models of cholestasis. Recent cloning of several canalicular transport systems now facilitates studies on their molecular regulation in cholestasis. Although the picture is far from complete, experimental evidence now exists that decreased or even absent expression of canalicular transport proteins may explain impaired transport function resulting in hyperbilirubinemia and cholestasis. With the increasing availability of molecular probes for these transport systems in humans, new information on the molecular regulation of canalicular transport proteins in human cholestatic liver diseases is beginning to emerge and should bring new insights into their pathophysiology and treatment. This article gives an overview on molecular alterations of canalicular transport systems in experimental models of cholestasis and discusses the potential implications of these changes for the pathophysiology of cholestasis.

ATP Binding Cassette Transporter, Subfamily B, Mem↗