[Incontinentia pigmenti or Bloch-Sulzberger syndrome. Apropos of a case in a male infant].
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Biomedical subjects
Publications and source records attributed to M Trabelsi.
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The authors report a retrospective study of 98 cases of idiopathic thrombocytopenic purpura in children. The sex ratio was 1/1 and the mean age 5 years. A history of viral infection preceded the purpura in 45% of the cases. Sudden onset was observed in 81%. The platelet count was less than 20,000 mm3 in 78.5%. A follow-up was obtained in 79 patients: 76% had an acute disease. A spontaneous remission occurred in 88.6% of the cases, most of them in the first six months (49 cases/68), and in 10 cases/68 between 7 and 11 months after onset. Six patients presented one or two relapses prior to recovery. The illness became chronic in 11% of the patients despite prednisone therapy. Four patients were treated by splenectomy, in 3 cases with success. Two children died, one girl from cerebral haemorrhage and one boy from septicemia.
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Based on 140 cases of typhoid fever observed in the pediatrics service of the Menzel Bourguiba hospital (Tunisia), the authors demonstrate that such an endemic disease still exists in rural areas, with a peak during autumn-winter season. They underline the importance of the contamination due to water. The disease strikes all groups of age. Infants represent 15% of the patients. On its clinical and biological aspect, the disease is significantly different in child or infant. Blood cultures are positive in 2/3 of the cases, while fecal cultures are positive only in 1/3 of the cases. Despite some complications occurring in 1/6 of the cases, evolution is generally favourable. However, infant septicemia is severe, causing death in 1/3 of the cases.