Famosa pestis and Britain in the fifth century.
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Disease↗
Biomedical subjects
M Todd
Publications and source records attributed to M Todd.
Medical assistants in the USA as viewed by the professions. The physician's view.
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American Medical Association↗
Anticoagulant malingerers (the "dicumarol-eaters").
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Adult↗
Kidney function in the octopus.
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Animals↗
Improved manufacture and application of an agarose magnetizable solid-phase support.
A simple, semiautomated, nonhazardous procedure for the production of a magnetizable solid-phase support (MSPS) has been developed based on the extrusion of molten agarose-iron oxide mixtures, which enables manufacture of a range of differently sized spherical agarose-iron oxide beads. This system has enabled scale-up of an original manufacture procedure and reproducible preparation of kg quantities of MSPS suitable for biomolecular purifications. An improved protocol for the isolation of plasmid DNA directly from cell lysates using this MSPS, derivatized with diethylaminoethyl (DEAE) groups, is reported. This involves a modified alkaline lysis, followed by adsorption to and elution from the support, yielding plasmid DNA of a purity comparable with, or better than, other methods of plasmid isolation. Using the same procedure, plasmid DNA can be isolated from bacterial cell culture volumes of 1.5 mL and 100 mL with equal efficiency and purity.
Chromatography, Gel↗
Early detection of genital chlamydial infection in women: an economic evaluation.
A decision analysis model was constructed for comparison of early detection of asymptomatic genital chlamydial infection in women by the direct immunofluorescence antibody (DFA) test and the enzyme-linked immunosorbent assay (ELISA) with no intervention. Early-detection programs using the DFA test and ELISA were shown to be cost-effective in female populations where the prevalences of chlamydial infection exceeded 6% and 7%, respectively. Sensitivity analysis showed that the two most important factors were the probability of developing pelvic inflammatory disease and the cost of the test. The DFA method was more appropriate for an early-detection program because of its higher sensitivity.
Chlamydia Infections↗
Who volunteers for adult development research?: research findings and practical steps to reach low volunteering groups.
The present study is an attempt to determine volunteering bias in racial, gender, and age groups in an adult development study. Samples were drawn from three different types of organizations in the Columbia, South Carolina SMSA. Volunteering rates were calculated as a function of the number eligible to participate in three age groups: young adult (aged 20-25); 2) middle adult (aged 40-45); and 3) old (aged 60-80). The middle group volunteered at a higher rate than the other two age groups, but this effect was restricted to the white sample. Women volunteered more readily than men, but not among the elderly. Whites volunteered more readily than blacks. In order to overcome these volunteering biases, special recruitment procedures were employed in order to obtain a sample which adequately represents the populations in question.
Adult↗
The management of a patient with lymphoedema of the legs.
Lymphoedema is a much under-publicised condition, yet it affects many people. Janice Bianchi and Marie Todd outline the implications of the condition and examine the treatment options of a typical case study.
Activities of Daily Living↗
National precedent for voluntary coverage of cancer treatment.
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Clinical Trials as Topic↗