TM4: a free, open-source system for microarray data management and analysis.
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Database Management Systems↗
Biomedical subjects
M Thiagarajan
Publications and source records attributed to M Thiagarajan.
Pupil block glaucoma in phakic and pseudophakic patients after vitrectomy with silicone oil injection.
PURPOSE: To describe pupil block glaucoma in phakic and pseudophakic patients after vitrectomy with silicone oil injection. DESIGN: Interventional case series. METHODS: Cases were collected from January 1997 to July 2000 from three tertiary referral centers. RESULTS: Seven phakic patients (seven eyes) and one pseudophakic patient (one eye) presented 1 to 90 days after vitrectomy and silicone oil injection with intraocular pressures of 36 to 70 mm Hg. Five patients had an observed or potential weakness of the iris-lens diaphragm. Treatment with Nd:YAG-laser peripheral iridotomy or inferior iridectomy provided a temporary reduction in intraocular pressure for some patients, but all eventually required removal of silicone oil. CONCLUSION: Pupil block glaucoma after silicone oil injection is well recognized in aphakic patients, but ophthalmologists should be aware that it can occur in phakic and pseudophakic patients, particularly in complicated cases and patients with a weakness of the iris-lens diaphragm.
Adult↗
Observations on T-cell sub-populations in type II reactions.
15 cases each of Type II Reaction, LL and TT Leprosy and 50 endemic controls were studied for phenotypic markers T2, T4 and T8 by 2 step immunoperoxidase technique. There was statistically significant increase in T4 (helper) cells in Type II Reaction. There was also a decrease in T8 cells but this was not statistically significant.
Adult↗
Paper spot test and DDS/creatinine ratios in relation to treatment taken by leprosy patients.
The findings on the positivity of paper spot test and the mean DDS/Cr. ratios in relation to the percentage of treatment taken by 316 leprosy out-patients on 100, 50 or 25 mg/DDS daily are presented. Thirty-three percent of the subjects on 25 mg were found to give negative spot test as against 11-12% in the patient groups on 50 and 100 mgs dose schedules. The mean DDS/Cr. ratios in the spot test negative urine specimens were consistent for all dosage groups and ranged from 7.1-9.6 micrograms/mg. The ratios in the spot test-positive urine specimens, showed, in general, a direct proportion to the percentage of treatment taken particularly, in the 75-100% and 50-75% groups. The significance and implications of the findings are discussed.
Creatinine↗