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Biomedical subjects

M Terzić

Publications and source records attributed to M Terzić.

At least 19 recordsLinked to original sources
PubMed2001

Laparoscopic management of consecutive ovarian pregnancy in a patient with infertility.

The diagnosis of ovarian pregnancy is based on the improper rise of serum beta-hCG levels, sonographic findings of an empty uterus, highly characteristic ovarian formation with double hyperechogenic ring surrounding small hypoechogenic field, and the laparoscopic verification of Spiegelberg's criteria. We present a case of ovarian pregnancy in spontaneous cycle in 34-year-old woman following two unsuccessful IVF/ET procedures and ovarian pregnancy on contralateral side laparoscopically treated seven months ago, also achieved in non-stimulated, spontaneous cycle. On admission she had a serum hCG level of 596 mIU/mL on cycle day 46 and an empty uterus. Transvaginal sonography showed a 20 mm ring-like thick-walled hyperechogenic structure within the left ovary. The echogenic ring was surrounded by irregular, hypoechogenic structures suggestive of an ovarian pregnancy with periluteal hemorrhage and blood clots. The ruptured cystic ovarian pregnancy and the corpus luteum were removed by laparoscopy. During the procedure we have seen two clips on the right ovary placed laparoscopically to achieve hemostasis after rupture of the ovarian pregnancy seven months ago. Histopathology showed isolated chorionic villi within hemorrhagic areas in the vicinity of the corpus luteum.

Adult↗
PubMed1996

The significance of aductal zones on pancreatograms: an anatomo-clinical assessment.

The authors analyzed 177 endoscopic retrograde pancreatograms (ERPs) with normal findings. The complete visualization of the side branches was achieved in 128 patients (72.3%), and aductal zones in the isthmus and mid-body of the pancreas were noted in 49 (27.3%) of these patients. The existence and incidence of the aductal zones were evaluated and verified in 141 anatomical duodenopancreas specimens. Thirty-two corrosion casts and 109 postmortem pancreatograms were analyzed. The postmortem specimens had a 36.2% incidence of aductal zones in the same location, with no statistically significant difference compared with the clinical pancreatograms. The visualization of the side branches was 100% on the postmortem pancreatograms, indicating that the clinical ERCP incidence of aductal zones is realistic.

Cholangiopancreatography, Endoscopic Retrograde↗
PubMed1995

The role of beta-endorphin in pregnancy and delivery.

This paper deals with beta-endorphin determination in 20 autopsy specimens of human fetal and neonatal pancreas, as well as in the placental tissue specimens of the same fetoplacental units, by means of radioimmunoassay (RIA-Nichols Institute). Peripheral blood samples of 10 healthy non-gravids were taken as controls. Our results present a marked increase of beta-endorphin levels with the progression of gestation, reaching a peak of 3960 pg/g at term. The data obtained indicate that beta-endorphin plays an important role in pregnancy and delivery regulation.

Female↗
PubMed1994

Is there a link between beta-endorphin and diabetes in pregnancy?

The possible influence of both beta-endorphin and insulin secretion on diabetes development in pregnant women was studied by means of radioimmunoassay technique (RIA-Nichols Institute). The study was carried out by determination of beta endorphins in peripheral blood samples of 28 pregnant women with gestational diabetes. They consisted of two subgroups: 14 women with insulin independence, and 14 with insulin-dependent disease. Beta endorphin increase was found in both groups, according to the progression of gestation, and the rise was significantly higher in the insulin-dependent group. At the same time, insulin application caused a marked growth of beta-endorphins in insulin-dependent group. Beta-endorphins, inhibiting insulin secretion, can influence gestational diabetes development.

Diabetes Mellitus, Type 1↗
PubMed1987

Oxygen consumption mediated by M2 muscarinic receptors in rat salivary glands.

Carbachol and oxotremorine stimulated the consumption of oxygen in rat parotid, submandibular, and sublingual gland slices in a dose-dependent manner. Their actions were abolished by atropine and nifedipine but not by trihexyphenidyl. The findings suggest that carbachol and oxotremorine enhanced oxygen consumption in the major salivary gland slices by the activation of the calcium-dependent muscarinic M2 receptors.

Animals↗
PubMed1984

The effects of epinephrine, norepinephrine, and carbachol on oxygen consumption in rat sublingual gland slices.

Epinephrine and carbachol, but not norepinephrine, significantly stimulated oxygen consumption in rat sublingual gland slices. The response to epinephrine was blocked by phentolamine and yohimbine, while propranolol and prazosin did not affect it. The response to carbachol was blocked by atropine. Also, oxygen consumption induced by both epinephrine and carbachol was inhibited by verapamil. These findings suggest that epinephrine enhanced oxygen consumption in sublingual gland slices by activation of alpha 2-adrenergic receptors, while carbachol activated muscarinic receptors; activation of both receptors mediated the respiratory response by facilitating the entry of extracellular Ca.

Animals↗
PubMedDate not supplied

[Laparoscopy in gynecologic oncology].

Using technological progress, laparoscopic lymphadenectomy is becoming a standard for staging of pelvic cancer. In the same way more extensive procedures such as para-aortic lymph nodes dissection and radical hysterectomy have been demonstrated to be feasible by laparoscopy. In the future, because of its well known advantages, laparoscopic surgery may appear as a way to decrease the consequences of oncologic treatments in patients with low risk tumors and to propose more aggressive treatments of patients with bad prognosis tumors.

Female↗