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Biomedical subjects

M Tasso

Publications and source records attributed to M Tasso.

17 recordsLinked to original sources

Outdoor background ELF magnetic fields in an urban environment.

Classification of 'exposed/non-exposed' subjects in epidemiological studies concerning the possible cancer risk associated with ELF magnetic field exposure is based on the a priori assumption of magnetic field value cut-off points that, often, are defined equal to minimum exposure levels typical of a population residing near high voltage facilities (0.1-4.2 microT), but in some cases an environmental magnetic field level not associated with transmission lines can exist. The results of an ELF magnetic field survey in an Italian urban area (about 1 million inhabitants) are presented: average field levels are correlated with population density of different districts. Exposure indexes are obtained, which are compared with those evaluated in studies regarding domestic exposure: background average levels result in comparable to cut-off points in epidemiological studies, but in some districts with high population density, they are much higher. This shows that knowledge of background magnetic field level in urban areas can assume a significant role in exposure assessment.

Background Radiation↗

Neuroblastoma and bronchogenic cyst: a rare association.

A few of the known associations between paediatric cancer and congenital anomalies are attributable to contiguous-gene syndromes. Neuroblastoma (NB) has been linked with an excess of gastrointestinal malformations, but there is a significant scarcity of associated respiratory anomalies. We report on two children having an abdominal NB and a bronchogenic cyst diagnosed simultaneously and in different order of appearance. Both masses were removed in separated procedures, taking into account the priority and the time sequence of chemotherapy. Literature is reviewed, checking that the genetic basis for this association is supported by speculations about the oncogene RON.

Adrenal Gland Neoplasms↗

Mortality of the German linguistic isolates of the western Italian Alps (Walser).

For five localities of Western Alps (Val d'Aosta and Piemonte) inhabited by Walser populations (Gressoney-la-Trinité, Gressoney St. Jean, Issime, Macugnaga and Rima) the main features of mortality are described, namely raw death rate, seasonality of deaths, distribution of deaths according to age classes and infant mortality. Death rate is higher than the Italian average value; seasonality of deaths shows some statistically significative differences only in a few decades and does not reach a high significativity. Distribution in age classes shows a rather low mortality at lower ages (0 and 1-4 years) with small changes between the two halves of the 20th century. An exception is constituted by Macugnaga, where an elevated mortality at lower age classes is present in both halves of the century, though higher in the first one. The picture can be considered as not typical of Walser populations. Infant mortality shows great variations in the investigated isolates, but an explication today is impossible. The degree of illiteracy, one of the causes of infant mortality, is rather elevated only at Macugnaga (until 1931). A comparison is made with other German linguistic islands studied so far by one of the two authors (G.M.).

Adolescent↗

Argyrophilic nucleolar organizer region counts and Ki-67 scores in human renal cell carcinoma.

The proliferative activity of 21 cases of renal cell carcinoma has been investigated by means of monoclonal antibody Ki-67 and Nucleolar Organizer Regions (AgNORs) analysis. The correlation between AgNOR counts and Ki-67 scores was only slightly significant (r = 0.53, r2 = 0.28) as determined by linear regression. Positive correlation was found between Ki-67 scores and tumour histologic grade. However, no correlation was observed between Ki-67 scores and tumour pathologic stage and between AgNOR counts and tumour histologic grade and/or pathologic stage. The results suggest that AgNOR counts cannot replace Ki-67 scores in evaluating the proliferative activity of renal cell carcinoma and that such activity and both histologic grade and pathologic stage seem to be independent parametres.

Analysis of Variance↗

Cow's milk intolerance and abdominal surgery: a puzzling connection.

We describe 9 infants (ranging from 1 to 6 1/2 months) in whom a surgical pathology (gastro-esophageal reflux and/or pyloric stenosis) was associated with cow's milk intolerance (CMI). In all cases vomiting and/or failure to thrive did not disappear after surgery. The patients recovered only after dietary manipulation by cow's milk protein free diet. In 5 out of 9 cases, multiple food intolerances were present (soy and/or casein hydrolysates). In all cases the diagnosis of CMI was confirmed by challenge test. The connections between CMI and abdominal surgery in infancy are discussed.

Animals↗