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Biomedical subjects

M Tanabe

Publications and source records attributed to M Tanabe.

462 records · Page 26Linked to original sources
PubMedDate not supplied

Glottal adjustment for regulating vocal intensity. An experimental study.

Living canine larynx was insufflated from the transected trachea with and without contractions of the lateral cricoarytenoid, cricothyroid and thyroarytenoid muscles, in order to study the control mechanism of vocal intensity at the glottal level. The contractions of the lateral cricoarytenoid and cricothyroid muscles were simulated with mechanical retraction, while the thyroarytenoid muscle was contracted with electrical stimulation. The vocal intensity (SPL), subglottal pressure and mean flow rate were measured simultaneously, and the aerodynamic power (pressure multiplied by flow rate) and the glottal resistance (pressure divided by flow rate) were calculated. At the same aerodynamic power, both the vocal intensity and resistance were increased by cordal adduction with contraction of the lateral cricoarytenoid muscle, whereas the vocal intensity was kept constant with contraction of the thyroarytenoid muscle in spite of increasing the resistance. Contraction of the cricothyroid muscle was inferred to influence the vocal intensity indirectly by altering the cordal adduction.

Air Pressure↗
PubMedDate not supplied

Perfusion, inhalation, and ventilation studies in patients with primary lung carcinoma.

To determine the relative roles of perfusion, inhalation, and ventilation lung scintigraphy, studies were done respectively in 48, 50, and 34 of 54 primary lung carcinoma patients (prior to thoracotomy and subsequent radical tumor resection). We observed the relationships between both the size of perfusion, inhalation, and ventilation defects observed scintigraphically, and the size of the mass lesion seen radiologically. We also estimated the correlation between those scintigraphic classifications and pTN. Although inhalation and perfusion images exhibited similar patterns, in hilar type lung carcinoma patients, the inhalation study showed superior mass lesion delineation. In peripheral type lung carcinoma, however, the incidence of negative inhalation defect (52%) differed significantly from that of negative perfusion defect (21%) (p less than 0.05). Xe-133 gas ventilation has limitations but is occasionally helpful in detecting obstructive airway disease. The coexistence ratio of COPD in lung carcinoma patients showed no significant difference from that of COPD in the controls. Perfusion and inhalation classification did not correlate with pTN factor.

Adenocarcinoma↗
PubMedDate not supplied

[Severe and fatal non-A non-B hepatitis in 4 young and children].

Four cases on non-A, non-B acute hepatitis have been observed in infants of the same family. No evidence of hepatitis A or B (HBs-Ag, anti-HBs antibodies, HBe-Ag, anti-HBe and anti-HBc antibodies) could be detected in sera. Virological investigations showed no evidence of cytomegalovirus, Epstein-Barr virus, infection, etc. The two younger infants developed disseminated intravascular coagulation and died. The other two recovered without sequelae.

Antibodies, Viral↗
PubMedDate not supplied

Bronchial and vascular supply in azygos lobe of inflated fixed lung: a case study.

Azygos lobe is a comparatively rare anomaly of the lung, and its radiologic features are well known. However, reports concerning its bronchial and vascular supply are few. The authors describe the bronchial and vascular supply of an azygos lobe in the autopsied right lung of a 43-year-old man. In the inflated fixed lung, the azygos lobe was supplied by the bronchi of the apical sub-subsegmental branch of B1b (B1bi) and B1a (B1ai) accompanied by the accompanied by the pulmonary artery of the same sub-subsegments (A1bi, A1ai). The lateral sub-subsegmental branches of B1aii and B1bii accompanied by the pulmonary artery did not supply the azygos lobe. The azygos lobe was supplied by V1a. V2 but not V1b.

Adult↗
PubMedDate not supplied

Transvenous embolization of high flow carotid cavernous fistula: a case report.

We treated a patient with a high flow traumatic carotid-cavernous fistula (CCF) by embolization using detachable balloons and metallic coils, by transarterial and transvenous approaches. The patient was a 20-year-old woman who had fractures in the skull base from a traffic accident. She was admitted to our hospital one month after the accident due to exophthalmos, chemosis, and periorbital bruit. Cerebral angiograms demonstrated left traumatic CCF and steal phenomenon of blood flow. Balloon embolization by transarterial approach performed three times was unsuccessful, probably because of balloon puncture due to bone fragments. Embolization using metalic coils via the superior ophthalmic vein route was then attempted. As a result of this approach, complete obliteration of CCF was obtained, and clinical symptoms subsided within a few days. Treatment of CCF by transvenous approach is one alternative when transarterial occlusion is difficult.

Adult↗
PubMedDate not supplied

CT-pathologic correlation in the tumor margins of lung cancer.

A CT-pathologic correlative study concerning the nature of the tumor margin was performed in 22 lung cancer cases with solitary nodules in the peripheral lung field. Three of 14 adenocarcinoma cases showed an ill-defined margin and an adjacent subtle high attenuation area on CT, representing alveoli lined by tumor cells. In the other 11 cases, both ill- and well-defined margins were seen on CT. A well-defined margin of the mass represented alveoli filled entirely with mucinous material or tumor cells. In three of six squamous cell carcinomas an ill-defined margin in CT represented the infiltration of lymphatic cells surrounding the tumor and continuous spread of tumor cells from neighboring alveoli. A well-defined margin in the other cases and two small cell carcinoma cases represented alveoli filled entirely with tumor cells. CT was shown to be very useful in the assessment of the nature of the margin of the tumor.

Adenocarcinoma↗
PubMedDate not supplied

Radiologic manifestation of spinal accessory neurinoma: a case report.

Spinal accessory nerve neurinoma is very rare; only 12 cases have been reported in the literature. We describe a 54-year-old woman who had a cisterna magna tumor expanding extracranially to the C1 cervical body. The tumor originated from the spinal root of the right accessory nerve. The radiological features including CT, MRI, and angiography are discussed. There have been reports on cranial MRI studies of spinal accessory neurinoma. MRI suggested an extra-axial tumor. The histological diagnosis was mixed Antoni A and B neurinoma. The neuroradiological findings of 12 cases of neurinoma of the accessory nerve reported in the literature are reviewed.

Accessory Nerve↗
PubMedDate not supplied

Rounded atelectasis formation following decrease of pleural effusion: a case report.

We present a case of rounded atelectasis (RA) observed continuously following decrease of pleural effusion. The collapsed right lower lobe adjacent to pleural effusion changed its shape from wedge-shaped consolidation with air-bronchogram to oval and flat formation at last. The vessels and bronchi curving into RA were detected by CT and we called it horizontal comettail sign. When a mass is detected following decrease of pleural effusion and vessels and bronchi are curving into the mass, the mass may be diagnosed as RA and no further examination may be necessary.

Bronchography↗
PubMedDate not supplied

A clinical comparison between Technegas SPECT, CT, and pulmonary function tests in patients with emphysema.

Pulmonary emphysema can be easily diagnosed by X-ray CT (CT) as low attenuation areas. Recently 99mTc Technegas has been used for ventilation scintigraphy. The present study was undertaken to assess the usefulness of SPECT images using Technegas scintigraphy and CT, as compared with pulmonary function tests in patients with pulmonary emphysema. Fifteen patients were examined. We classified and defined the score according to the findings of Technegas scintigraphy (Technegas) images into four grades, from Score 0 to Score 3, and those of CT into five grades, from Score 0 to Score 4, both from normal to severe. The right lung was divided into nine segments, and the left into eight. To obtain the average of the entire lung, the total score from both lungs was divided by 17. These average scores in for SPECT and CT were compared with the results of pulmonary function tests. The average score of Technegas correlated well with % forced expiratory volume in one second (%FEV1.0) (r = 0.87), and forced expiratory volume in one second % (FEV1.0%) (r = 0.83). These results were better than those provided by CT. The average scores of the upper and lower lung fields were also calculated. The score in the upper lung field was higher than that in the lower field. Technegas can assess ventilation impairment in pulmonary emphysema more easily than CT, especially in the upper lung field.

Administration, Inhalation↗
PubMedDate not supplied

Effect of chemotherapy on Tl-201 tumor uptake: experimental study.

The purpose of this study was to investigate the correlation between histopathological changes and 201Tl accumulation in tumor following chemotherapy in the evaluation of chemotherapeutic effect. Walker 256 carcinoma implanted in the right thighs of Wistar rats was treated by the intravenous injection of adriamycin (ADR). 201Tl scintigraphy was performed before and 12, 24, 72, and 96 hours after chemotherapy. The count ratio of tumor to normal muscle (T/N ratio) was measured by gamma camera. Tumor growth rate was measured and histopathological examination of the tumor after 201Tl scintigraphy was performed. The tumors of all rats disappeared within 2 weeks after chemotherapy, but the T/N ratio did not change. Histopathological findings showed a decrement of tumor cells, small necrotic regions, and remarkable lymphocyte infiltration in the tumor bed in the healing stage. After 201Tl injection, lymphocytes isolated from tumor tissue showed noted 201Tl accumulation. These results suggest that the T/N ratio did not decrease after ADR chemotherapy because of the accumulation of 201Tl in lymphocytes. We concluded that the use of 201Tl may underestimate the therapeutic effect of ADR.

Animals↗
PubMedDate not supplied

CT angiography with helical CT in the assessment of acute stage of subarachnoid hemorrhage.

PURPOSE: We evaluated the usefulness of helical CT in the preoperative assessment of ruptured cerebral aneurysms during the acute stage of subarachnoid hemorrhage (SAH). METHODS: Nine patients with 13 aneurysms were included in this study. Helical CT scanning was performed before preoperative angiography. The section thickness and the table-movement speed were 1-2 mm/sec. Helical CT scanning was started 20 sec after the start of injection of 100 ml of contrast agent at a rate of 3 ml/sec. RESULTS: The average CT value of SAH was 51.9 Hounsfield units (HU) and that of the aneurysm was 191.7 HU. Nine of 13 aneurysms greater than 3.0 mm in diameter were identified by three-dimensional CT angiography (3DCTA). In seven cases, the information provided by 3DCTA images, maximum intensity projection images, and multiplanar images, was very useful in surgical planning, providing information concerning the configuration of the neck and relationships between the aneurysm and brain parenchyma. Four aneurysms in two cases were not depicted by 3DCTA because they were located outside the imaging volume. This problem was overcome by changing the imaging volume according to the extent of origin of SAH. CONCLUSION: We conclude that helical CT in patients with SAH is useful for surgical planning, providing valuable information that cannot be obtained by conventional angiography.

Acute Disease↗