Search PubMed⌕ Search

Biomedical subjects

M Takeuchi

Publications and source records attributed to M Takeuchi.

At least 955 records · Page 53Linked to original sources
PubMed1982

Polarcardiographic study of inferior myocardial infarction: global projection of heart vector.

The sensitivity of electrocardiographic, vectorcardiographic and polarcardiographic criteria for inferior myocardial infarction was studied. ECG and Frank system VCG were recorded in 50 normal cases and 40 cases of inferior myocardial infarction, whose acute phase was documented by typical electrocardiographic and serum enzymatic changes. The records were made from one month to 16 years after acute attacks. Polarcardiograms were obtained by a specially-designed analogue computer from X, Y and Z signals of the VCG, and recorded at a paper speed of 1000 mm/sec by Mingograph. The polarcardiographic tracings were measured at every 5 msec after onset of the QRS wave, and plotted on the Aitoff's equal-area projection. In normal cases, the QRS vectors plotted on Aitoff's projection passed through the narrow area between 15 to 35 msec after the QRS onset. Electrocardioraphic diagnosis of myocardial infarction was correctly made in 22 cases (55%), and by VCG the sensitivity was improved to 32 cases (80%). Polarcardiographic diagnosis was made in 33 cases (82.5%). Global plots of heart vector on Aitoff's projection were a useful display to visualize the sequential changes of heart vector. In inferior myocardial infarction, the QRS vector passed through the more superior portion to normal, and the diagnosis was accurately made in 33 cases (82.5%).

Adult↗
PubMed1982

Computerized tomography of the kidney: tissue-plasma ratio of contrast enhancement with bolus injection and renal function.

Computerized tomography can be used not only for morphological studies but for physiological ones as well. Using computerized tomography, we were able to observe changes in renal parenchymal flow rates, with the aorta and renal parenchyma as regions of interest. There were 62 studies performed on 48 patients with and without known renal disease. The change in the tissue-plasma ratio with the use of contrast medium in 124 renal units correlated well with the renal function observed on excretory urography. The 14 patients subjected to renal ischemia during surgery underwent computerized tomography before and after the operation. The change in the tissue-plasma ratio of those kidneys operated upon was decreased significantly postoperatively compared to values found for the nonischemic contralateral kidneys. The results were reproducible and suggest that computerized tomography can be used as a method of evaluating the renal function per unit of parenchymal volume.

Contrast Media↗
PubMed1982

Measurement of renal parenchymal volume using computed tomography.

In hydronephrosis, total renal volume is not correlated with renal parenchymal volume. We have used computed tomography (CT) to determine renal parenchymal volume in 17 control patients and 36 patients with unilateral hydronephrosis. An additional 17 patients were studied before and 2 weeks after renal surgery. Renal parenchymal volume was determined by summing up the parenchymal area in each scan, taken at 10 mm intervals. Renal parenchymal volume measured by CT correlated well with renal area on excretory urography in normal kidneys. Renal parenchymal volume in hydronephrosis, however, was totally unrelated to renal area on excretory urography because of the grossly dilated calyceal system. Reproducibility of this study was ascertained in 17 patients using the contralateral nonoperated kidneys before and after the surgery (r = 0.939; p less than 0.01).

Humans↗
PubMed1982

[Carcinogenicity study of cholestyramine in mice].

Carcinogenicity study of cholestyramine, an anti-hypercholesterolemic agent, was carried out by feeding B6C3F1 mice of both sexes with the pellet diet in which cholestyramine was admixed at the rates of 1.25, 2.5 and 5%. The animals were fed on the drug-admixed diet for 18 months and on a normal diet for subsequent 3 months. After 32 weeks the mortality of male mice began to increase in the 5% cholestyramine group and the number of dead or moribund mice increased markedly after 60 weeks. Hemorrhage recognized in pleural cavity, heart and other organs, was suggested to be the main cause of death. Some kinds of tumors occurred in each group, but the tumor-incidences seen in mice of 1.25 and 2.5% cholestyramine groups were similar to those in mice of the control group and the occurrence of the specific tumor or an acceleration of tumor-development by feeding cholestyramine were not observed. Furthermore, the tumor-incidence in mice fed on the 5% cholestyramine diet was less than that in mice of the other three groups.

Animals↗