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Biomedical subjects

M Takebayashi

Publications and source records attributed to M Takebayashi.

49 records · Page 3Linked to original sources

[A histopathological study of gastric cancer with liver metastasis, with special reference to poorly differentiated adenocarcinoma of the medullary type].

Thirty-nine gastric cancer patients with liver metastasis on laparotomy were histologically analyzed. Poorly differentiated adenocarcinoma of the medullary type was the most common histologic type followed by papillary adenocarcinoma. Analysis of 32 gastric cancer patients who manifested liver metastasis after the operation showed that papillary adenocarcinoma and poorly differentiated adenocarcinoma of the medullary type were frequent. We conclude that poorly differentiated adenocarcinoma of the medullary type is the most common histologic type of gastric carcinoma metastasizing to the liver.

Adenocarcinoma↗

Follow-up study on the cause of death after surgery for gastric and duodenal ulcers with special reference to the incidence of residual stomach cancer.

Of 1325 patients operated for gastric or duodenal ulcer between 1948 and 1977, 295 (22.3%) had died. We analyzed the cause of death in these patients by follow-up study. The 3 major causes were cerebro-, cardiovascular and malignant disease, the same as in the normal Japanese population. In patients with malignant diseases, death was due to cancer of the liver, lung and remnant gastric stump in 6.0%, 5.2% and 0.4%, respectively. Compared to Western countries, the incidence of cancer of the gastric remnant was remarkably low in our series.

Adult↗

Possible role of lymph node dissection in the surgical treatment of gastric cancer with disseminating peritoneal metastasis.

qathological background factors of patients with gastric cancer and peritoneal metastasis were studied. In palliatively gastrectomized patients, there was a close relationship between the extent of cancer invasion to the gastric serosa and postoperative survival; the less extensive the serosal invasion, the longer was the survival time. The relationship between the extent of lymph node dissection and postoperative survival showed that, in the presence of metastasis to Group 1 and 2 lymph nodes, many of the long-term survivors had undergone dissection of these lymph nodes. Although a sweeping conclusion should be avoided since retrospective analysis forms the basis of this report, it is assumed that in patients with gastric cancer and peritoneal metastasis, surgery should not be confined to resection of the primary focus, but should include regional lymph node dissection.

Adult↗

Lymph node removal for advanced gastric cancer with special reference to peritoneal metastasis.

The 5-year survival rate of gastric cancer patients was evaluated in relation to cancer infiltration to the gastric serosa, lymph node metastasis and lymph node removal, the pattern of cancer recurrence, and the presence of free cancer cells in the peritoneal cavity. The 5-year survival of patients with cancer infiltration to the gastric serosa was not improved even by more extensive lymph node removal (R3 removal) than secondary lymph node removal (R2 removal). In these patients, viable free cancer cells were detected in the peritoneal cavity. In patients with cancer recurrence, peritoneal metastasis was often present within 2 years of curative surgery. Based on our present results, we suggest that in advanced gastric cancer with marked serosal invasion, selective removal of more distant lymph nodes than secondary lymph nodes according to the location of the primary cancer lesion should be carried out in addition to R2 removal and that this selective removal is superior to uniform R3 removal.

Humans↗

[Metastasis of gastric cancer to the spleen--a case report].

Metastasis to the spleen is often found in cases with malignant hematologic disorders. To our knowledge, however, few survivors with primary gastric cancer and splenic metastasis have been reported. A 64-year-old woman underwent curative total gastrectomy combined with pancreaticosplenectomy for gastric cancer, Borrmann III type, in the upper body of the stomach and cardia. Postoperative histologic examination revealed that the poorly differentiated adenocarcinoma had metastasized to the spleen. The low incidence of splenic metastasis from gastric cancer may be a reflection of special antineoplastic traits of the spleen related to phagocytic qualities, or to humoral factors which are as yet unidentified.

Adenocarcinoma↗