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Biomedical subjects

M Tada

Publications and source records attributed to M Tada.

At least 685 records · Page 38Linked to original sources
PubMedDate not supplied

Endoscopic treatment of early gastric cancer.

Laser therapy and endoscopic strip biopsy for early gastric cancer are useful measures from our experience. It is considered that the larger lesion of early cancer should be treated by laser therapy and the smaller lesion by strip biopsy. However, endoscopic therapy as a curative treatment still presents problems. Clinical trials with laser therapy has to accumulate to ascertain the effectiveness of laser on the gastric wall. Also, endoscopic treatment methods are limited to patients who cannot be admitted to surgery. Furthermore, it is difficult to judge the metastasis to lymph nodes surrounding the stomach with present diagnostic capabilities. Wider application of these endoscopic treatment methods will follow when these difficulties are overcome.

Adenocarcinoma↗
PubMedDate not supplied

Massive plexiform neurofibroma in the orbit in a child with von Recklinghausen's disease.

We report a case of orbital plexiform neurofibroma presenting in a 10-year-old boy with von Recklinghausen's neurofibromatosis. The patient had shown a slow enlargement of exophthalmos of the right eye present since birth, together with multiple café au lait spots on the skin of the trunk. Magnetic resonance (MR) images revealed diffuse and irregular nodular involvement of the retrobulbar nerves within the muscle cone, which was confirmed at the surgery. The tumour extended into the ipsilateral cavernous sinus. We discuss the MR findings as pathognomonic signs of this rare orbital tumour, including its multinodular nature among dispersed intraconal fat tissue, location around the optic nerve, extension through the superior orbital fissure into the cavernous sinus and association with von Recklinghausen disease.

Child↗
PubMedDate not supplied

Endoscopic therapy for early colon cancer: the strip biopsy resection technique.

Strip biopsy is an endoscopic tissue resection technique in which a lesion and its surrounding tissues are first elevated using physiological saline. The saline solution is injected into the submucosa at the site of the lesion with the help of needle forceps. A snare is placed around the elevated tissue, which is then resected endoscopically by electrocoagulation. The specimen obtained includes both submucosal and mucosal tissues. The authors used this technique to resect a total of 71 lesions of the colon. They were classified histologically as 21 adenocarcinomas, 46 adenomas, 3 metaplastic polyps, and 1 juvenile polyp. All lesions were confirmed to be entirely intramucosal by histological examination. The strip biopsy technique permits resection of tissue down to the submucosal layer regardless of the morphological type of the lesion. This suggests that strip biopsy is an effective new form of endoscopic treatment for early colon cancer.

Adenocarcinoma↗
PubMedDate not supplied

Delineation of the gastric muscularis mucosae and assessment of depth of invasion of early gastric cancer using a 20-megahertz endoscopic ultrasound probe.

Using a 20 MHz endoscopic ultrasound system, delineation of the gastric muscularis mucosae and estimation of the depth of malignant invasion was attempted by in vivo scanning during the process of routine endoscopic observation or in vitro scanning of excised sections of 34 early gastric cancers in 32 patients. The muscularis mucosae was visualized as a single hypoechoic layer in 16 of 32 lesions (50%) scanned in vitro. Comparison of lesions in which delineation of the muscularis mucosae was or was not possible revealed no significant differences with respect to either the thickness of the lamina propria and muscularis mucosae or with respect to the degree of inflammatory cell infiltration of the lamina propria or the conditions of the boundary between the lamina propria and the muscularis mucosae. This indicates that improvement of the operability characteristics of the ultrasonic apparatus will be needed to achieve improved delineation of the muscularis mucosae. The accuracy of invasion depth estimation of early gastric cancer was 67% (16 of 24 lesions scanned in vivo) and 73% (8 of 11 lesions) in cases in vivo where the muscularis mucosae and the tumor were delineated on the same screen. The principal factors causing erroneous staging were the presence of dilated benign glandular ducts, ulcer scars, and attenuation of the ultrasound waves.

Aged↗