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Biomedical subjects

M T Stechison

Publications and source records attributed to M T Stechison.

28 records · Page 2Linked to original sources
PubMed1990

Cervical myelopathy in diffuse idiopathic skeletal hyperostosis. Case report.

The case of a rapidly progressive cervical myelopathy in a 64-year-old man is presented. Radiological studies revealed a partial extradural block, which at surgery was found to be a focal fibrous, calcified mass associated with the ligamentum flavum. On the basis of the underlying disorder of diffuse idiopathic skeletal hyperostosis (DISH), the etiology of this compression was concluded to be focal fibrous proliferation and dystrophic calcification. The neurological complications of DISH are reviewed. The authors are not aware of any other reports of this cause of myelopathy associated with DISH.

Calcinosis↗
PubMed1989

Spinal extradural arachnoid cyst.

A relatively unusual cause of progressive paraparesis is a spinal arachnoid cyst. The following is a case report of this lesion in an adolescent. The CT-myelographic and MR features, as well as the management of this case are discussed, followed by a review of the pertinent English literature on this topic.

Adolescent↗
PubMed1987

A transcervical surgical approach to the ventral medulla of the cat.

For the purpose of injection of anatomical tracers, it is desirable to have a surgical approach which provides the most direct approach to the target structure. This minimizes the amount of neural tissue that must be transgressed, and hence the leakage of tracer along the tract and the potential undesirable labelling that may result from this. In addition, visual guidance is preferable to stereotaxic guidance of injections where possible, particularly in situations where the target structure is far removed from the ear bar zero coordinate. Some of our work has necessitated small, discrete injections in the inferior olive sparing the adjacent reticular formation. The ventral transcervical approach to the medulla which was developed for this purpose is described below. It may conceivably be of use to physiologists wishing to record from ventral medullary structures. We feel it is a useful technique, but one which those with little surgical experience might not attempt. It is hoped that our description may guide others who could benefit by this approach.

Animals↗
PubMed1987

Spinal meningioma en plaque. Report of two cases.

Two cases of spinal meningiomas exhibiting en plaque patterns of growth are presented, one of which is reviewed more fully with emphasis on the radiographic and histological characteristics. The difficulties in diagnosis of this unusual tumor, its surgical management, and its postoperative course are discussed.

Aged↗
PubMed1986

Organization of spinal inputs to the perihypoglossal complex in the cat.

First- and second-order spinal afferents to the perihypoglossal complex were sought by using axonal transport of WGA-HRP. Injections in C1, 2, and 3 dorsal root ganglia resulted in axonal labeling in the nucleus intercalatus and the external cuneate nucleus, with a number of retrogradely labeled cells seen as well in the latter. A similar pattern of axonal labeling in the nucleus intercalatus as well as several retrogradely labeled cells were found after spinal cord injections at levels C1, 2, and 3. A prominent field of labeled axons was also present in the rostral main cuneate nucleus. No labeling was seen in the perihypoglossal nuclei after injections in the spinal cord or dorsal root ganglia at levels caudal to C3. After injections of HRP into the perihypoglossal nucleus we were able to identify labeled neurons within Rexed's laminae V-VIII and the central cervical nucleus. Anterograde labeling in the main cuneate nucleus was observed after C1 to C5 ganglion and C1 to C6 cord injections. The pattern and extent of labeling in the perihypoglossal nuclei and adjacent structures seen after cerebellar injections into lobules V and VI were comparable to those previously reported and permitted evaluation of the relay from dorsal root ganglia through the intercalatus to the vermis. Topography of the cervical projections to the nucleus intercalatus is considered with respect to that of the perihypoglossal-collicular projection. A discussion is offered of the apparent importance of nucleus intercalatus as a relay of cervical and vestibular afferent information to premotor structures involved in neck motor control. The perihypoglossal complex is viewed as being organized in such a fashion as to allow the nuclei intercalatus and prepositus hypoglossi to function as key structures in the integration of inputs related to neck and ocular motor control, respectively.

Afferent Pathways↗
PubMed1985

Projections from the nuclei prepositus hypoglossi and intercalatus to the superior colliculus in the cat: an anatomical study using WGA-HRP.

In view of the recognized role of the superior colliculus (SC) in eye and head movement, and following recent physiological studies, the presence of afferents to the SC from the vestibular complex and adjacent cellular groups were sought using axonal transport techniques. Injections of wheat germ agglutinin conjugated to horseradish peroxidase (WGA-HRP) were made in the SC of 9 adult cats. Retrogradely labelled cells were observed in the nuclei prepositus hypoglossi (PH) and intercalatus (INT) predominantly contralaterally with only occasional cells in the medial (MVN) and descending (DVN) vestibular nuclei contralaterally. There appeared to be some topographical differences in anteroposterior distribution of labelled cells in the perihypoglossal nuclei after restricted SC injections. Two cases of intramedullary injection of WGA-HRP which involved the PH, INT, MVN and DVN revealed anterogradely labelled terminations in laminae IV and VI of the contralateral SC. A few additional labelled terminations were found in the medial portion of the contralateral medial geniculate body (MGB) and the nucleus of the optic tract-(NOT). The possible role of the perihypoglossal nuclear complex as a site of convergence of vestibular and neck afferent inputs destined for the SC is discussed.

Animals↗
PubMedDate not supplied

Meningioma in congenital adrenal hyperplasia.

A diversity of malignancies have been reported in patients with congenital adrenal hyperplasia. We report a case of multiple meningiomas, tumors which are more common in females and reported to have sex steroid receptors, in a 46,XX male (severe female hermaphrodite raised as a male) with 21-hydroxylase deficiency. The patient has been treated with glucocorticoids since 3 years of age and testosterone since puberty.

Journal Article↗