Biomedical subjects
M T Le Cam
Publications and source records attributed to M T Le Cam.
[Atrial myxoma: cutaneous manifestations].
INTRODUCTION: Atrial myxomas may have variable misleading symptoms, explaining frequent delays in diagnosis. Multiple embolisms with irreversible consequences may occur. The dermatologist has a prominent role to play, as the clinical picture includes cutaneous signs. CASE REPORT: A 60 year old woman, with previous history of joint pain and Raynaud's phenomenon suffered a sudden neurological transitory ischemic event. The cutaneous manifestations associated left forearm erythematous macules, distal ischemia of the left fourth and fifth fingers and livedo of both lower limbs. Cardiac echography confirmed the clinical diagnosis of atrial myxoma. Surgical excision was followed by rapid and complete cure. DISCUSSION: Atrial myxoma is a rare benign tumor usually revealed by prominent cardiac and embolic manifestations. Systemic and cutaneous signs may however be the sole symptoms, warranting the dermatologist's attention.
[Acute mast cell leukemia disclosed by vasomotor flushing].
INTRODUCTION: Acute mast cell leukemia is a rare and severe disease. We report herein a case associated with a flush syndrome. CASE REPORT: A 44-year-old man, presented with a flush of face and trunk. Bone marrow was infiltrated with immature mast cells. In spite of chemotherapy and bone marrow transplantation the patient deceased. DISCUSSION: Pheochromocytoma, carcinoid tumor, and mastocytosis are associated with a flush syndrome. In our patient the diagnosis was an acute mast cell leukemia. Acute mast cell leukemia can follow systemic mastocytosis or occur de novo. This disease is of poor prognosis. No treatment is available.