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Biomedical subjects

M Swerdloff

Publications and source records attributed to M Swerdloff.

At least 19 recordsLinked to original sources
PubMed1990

Mucous cell hyperplasia in an odontogenic cyst from a patient with Muir-Torre syndrome.

Mucous cell proliferation in a periapical radicular cyst from a patient with a family history of colonic malignancies and multiple sebaceous neoplasms of the skin, so-called Muir-Torre syndrome, is reported. Such goblet cell hyperplasia has not been previously reported to be associated with any known syndrome. We believe the finding of mucous cell hyperplasia in an odontogenic cyst may not simply be coincidental, but should raise suspicion of paraneoplastic potential and warrant further evaluation for possible occult neoplastic disease.

Adult↗
PubMed1980

Mental nerve neuropathy: a complication of sickle-cell crisis.

Anesthesia of the mental nerve, a rare complication of sickle-cell disease, has been reported. This is the first documented and reported case occurring in the United States. A review of the basic pathophysiology of the disease has been presented.

Adult↗
PubMed1980

Effect of fixation upon the histochemistry of glycosaminoglycans (mucopolysaccharides) in intraoral wounds.

Intraoral wounds and biochemical films were examined to determine the best method of fixation for glycosaminoglycans. Tissues fixed in 1% cetyl pyridinium chloride-10% formalin stained intensely with preparations of Alcian blue. When these tissues were treated with Streptomyces hyaluronidase and bacterial chondroitinases, staining was comparable to untreated tissues fixed in only 10% formalin. The addition of cetyl pyridinium chloride to formalin fixatives was a requirement for glycosaminoglycan histochemistry in open wounds, and presumably in other tissues that contain these complex sugars.

Alcian Blue↗
PubMed1980

Mucopolysaccharidase activity in traumatized human deciduous teeth undergoing accelerated resorption: isolation and characterization.

Mucopolysaccharidase activity was observed in traumatized human decidous teeth. Histochemical analysis of the periodontal ligaments from these teeth revealed a loss of film substrate metachromasia during incubation, indicating enzyme activity. Routine histology of these ligaments showed the presence of an inflammatory infiltrate throughout this tissue. Biochemical analysis of the ligaments revealed a 10-fold increase of enzyme activity when incubation time was increased from 1 to 8 h. When compared to the enzyme activity measured during physiologic resorption, activity was increased. This suggests that the presence of an inflammatory infiltrate not observed in the tissues undergoing physiologic resorption may be responsible for the rapid resorption seen in traumatized deciduous teeth.

Child↗
PubMed1980

Identification and localization of a mucopolysaccharidase in human deciduous teeth.

The presence of a mucopolysaccharidase in resorbing deciduous teeth was investigated using histochemical techniques. The loss of toluidine blue metachromasia within glycosaminoglycan film substrates indicated the presence of enzyme activity, and was related to physiologic resorption. Such activity was localized to the periodontal ligament of these teeth.

Adolescent↗
PubMed1980

Dental pulp mucopolysaccharidase: identification and role in tooth resorption.

The presence of mucopolysaccharidase activity within the pulps of resorbing deciduous teeth was investigated using histochemical techniques. The loss of toluidine blue metachromasia within glycosaminoglycan film subtrates indicated the presence of enzyme activity. This was related to physiologic resorption.

Adolescent↗
PubMed1980

Systemic lupus erythematosus.

A case of osteomyelitis of the mandible in a patient with systemic lupus erythematosus is described. Both the disease process and the treatment modalities must be understood for correct management.

Adult↗
PubMed1980

Elastic tissue in early intraoral wounds.

Histochemical analysis of elastic tissue in early intraoral healing of wounds demonstrated that these fibers were concentrated in the perivascular areas of granulation tissue and within newly formed connective tissues at the base of the wound. These results were consistent with previous reports indicating that the cellular origin of this tissue is smooth muscle cells or fibroblasts.

Animals↗