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Biomedical subjects

M Stulhofer

Publications and source records attributed to M Stulhofer.

At least 19 recordsLinked to original sources

Papers published by members of the Croatian Academy of Medical Sciences, registered in international bibliographic data bases in the period 1986-1990.

Scientific productivity of the CAMS members was analyzed according to the number of papers published in periodicals covered by international Medline and Science Citation Index data bases from 1986 to 1990. Results showed the mean scientific productivity per CAMS member, and the relationship between scientific productivity and age, field of medicine or respective biomedical discipline. The pattern of scientific productivity was also found to change, when analyzed according to Medline or SCI data bases in separate.

Bibliometrics

["Stress" ulcer - acute ulcerous and erosive lesions in the gastroduodenal mucosa].

Acute gastroduodenal mucosal lesions are observed following shock, sepsis, trauma, bat also after the ingestion of certain substances (alcohol) and in the course of severe, chronic medical illness. The so-called cushing ulcus should probably be separated from the clinical syndrome of stress ulcer. We must also exclude without any discussion reactivated chronic duodenal or ventricular ulcers with their complications, often manifested after serious trauma or illness. Digestive complaints are absent from the history of illness. The earliest manifest sign is in most cases severe gastrointestinal haemorrhage. It appears that the presence of Hydrogen ions in gastric contents and mucosal ischaemia are required for stress ulcer to develop, in which process damage to the "mucosal barrier" is also instrumental. The basic diagnostics is endoscopy. Angiography is only indicated in patients where endoscopy has failed. Conservative therapy brings haemorrhage under control in most cases. Surgery is indicated only if conservative therapy has proved inadequate to control bleeding or in cases of free perforation. Optimal surgical treatment remains a matter of discussion since no surgical method, except total gastrectomy, can protect the patient from recurrent haemorrhage.

Humans

[Correlation of gastroscopic, pathohistologic, cytologic and cytochemical analysis of ulcer lesions and other pathologic changes in the gastric mucosa. Preliminary study].

This paper concerns our first experience of correlation analysis between the gastroscopic, pathohystologic, cytologic and cytochemical findings of different organic gastric lesion on gastroscopy. The authors' experience is based on 78 patients in whom 450 biopsies were performed. For an adequate analysis, 135 samples of pathohystologic anc cytological examinations were useful and only 80 samples for cytochemical analysis. From these examinations it is possible to conclude that the cytochemical reactions of the group of patients with inflammatory lesions and intestinal metaplasia showed changes in the level of enzyme aminopolypeptidase together with the presence of acid mucopolysacharides. In the group of patients with lesions showing an ulcer, carcinoma or suspect malignancies, the changes occured in the composition of enzymes such as acid phosphatase, DNP Diaphoresis and nonspecific esterases. With such combined examinations the percentage of correct diagnoses was increased in comparison with conventional method of gastroscopy and biopsy.

Gastric Mucosa

[Partial pancreatectomy in modern surgical practice].

In modern surgery, the pancrectomy is an operation indicated in a wide number of cases. Indications for such a procedure that were once limited to malignant lesions of the papilla of vater and the head of the pancreas now include chronic pancreatitis, some benign lesions of the duodenopancreatic area, and serious cases of acute necrotizing pancreatitis. Thanks to Modern surgical technique especially in anesthesia, reanimation, and postoperative care, the mortality rate in the partial pancrectomy is Recured to a rational number. Nonetheless, postoperative exiturs cannot be neglected. As a result it is necessary to consider strict indications for a pancrectomy. Only under such conditions can satisfactory therapeutic results be achieved.

Humans