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Biomedical subjects

M Stejfa

Publications and source records attributed to M Stejfa.

At least 73 records · Page 4Linked to original sources
PubMed1977

[Instable angina pectoris and the pre-infarct condition].

The instable angina pectoris belongs to the prodromes of an acute transmural my ocardial infarction, to which we refer every fresh angina pectoris, increase and prolongation of the anginous pain after stress and the appearance of pain in rest. Retrospectively we established the instable angina pectoris in 45% of the cases of a transmural myocardial infarction. Prospectively the syndrome of the instable angina pectoris was followed by a transmural myocardial infarction in 18%. In 14% of the cases with instable angina pectoris without provable transmural myocardial infarction a sudden heart death took place. In the discussion the author deals with questions of the not clarifyed pathogenesis and therapy. The instable angina pectoris is, indeed, an important clinical syndrome, but from the point of view of the short-time prognosis in our opinion it has not the presumed significance for the development of the transmural myocardial infarction and the sudden heart death.

Acute Disease↗
PubMed1977

A noninvasive study of the response of ischemic heart to exercise.

The response to exercise during increasing workloads (supine bicycling), was studied in 105 men, of whom 70 had ischemic heart disease and 35 did not, clinically classed into 6 groups. Heart rates, blood pressures and systolic time intervals (STI) were measured in relation to exercise tolerance and capacity. The ischemic heart disease (IHD) subjects differed from the nonischemic by an increased PEP/LVET ratio at rest and by a tendency of the diastolic blood pressure to increase upon exercise. Two main types of abnormal reaction of STI to workload were ascertained: (1) prolonged LVETc with respect to controls (prevailing in angina pectoris), and (2) prolonged PEPEc together with shorter LVETc (typical for left ventricular failure). The dominant feature appears to be the depressed contractility in the latter and a decreased compliance (or rate of relaxation) in the former. Estimation of STI may contribute to the evaluation of the exercise tolerance test in long-term examination of ischemic patients.

Adult↗