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Biomedical subjects

M Stejfa

Publications and source records attributed to M Stejfa.

At least 37 records · Page 2Linked to original sources
PubMed1991

[Angina pectoris revisited].

Based on data in the literature and his own experience, the author presents modern views on angina pectoris. He discusses anamnestic signs of typical and atypical angina and non-anginous chest pain. He mentions the pathogenesis and clinical picture of stable angina (secondary and mixed angina, syndrome X), unstable angina (mixed and primary angina) and silent ischaemia. As to examinations, he emphasizes in addition to the case-history the importance of the objective finding and stress tests. On the latter indications for invasive examinations are based. The author recapitulates treatment, prognosis an assessment.

Angina Pectoris↗
PubMed1990

[Is accurate dosing possible using infusion sets?].

The authors discuss factors which influence the dispensing of infusion solutions by means of infusion sets regulated by a button. They draw attention to the fact that by means of infusion sets IS 103 and TS 203 accurate dispensing is not possible as the rate of flow changes markedly with the time of administration of the infusion. On the other hand, in the EXADROP dispenser marked slowing down of the infusion in relation of time does not occur and the authors recommend it therefore for common use in standard departments.

Humans↗
PubMed1990

[Practical use of infusion pumps].

The authors present a brief characteristic of infusion pumps on the drop principle and factors which influence the size of the drop. They also pay attention to the knowledge of drop size for nutritional needs and accurate dosage of drugs.

Infusion Pumps↗
PubMed1989

[The development and use of nitrate therapy].

The authors describe the development of nitrates from substances of the first generation (nitroglycerin and isosorbide dinitrate) to the use of mononitrates. They explain the mechanism of their action, the haemodynamic effects and the phenomenon of nitrate tolerance. The authors present also their own experience with nitrate therapy in angina pectoris and heart failure based on haemodynamic monitoring and recommend its rational use.

Chemical Phenomena↗
PubMed1989

[Clinical effects of isosorbide dinitrate in the transdermal spray (TD Spray Iso Mack) form].

The authors report on their experience with the transdermal spray, TD spray Iso Mack. Using a graded ergometric test, the authors examined 11 patients with angina on exertion before and 60 minutes after administration of 60 mg of the effective substance by the transdermal route. The average threshold of ischaemia and work tolerance increased significantly and the ECG depression of segment S-T receded. In an open trial six patients were investigated with angina on exertion during three-week treatment with the spray--twice a day 60 mg by the transdermal route--as compared with standard treatment. The number of attacks and consumption of sublingual nitroglycerin decreased significantly. Five patients were subjected to haemodynamic examination before and repeatedly after application of 60 mg of the spray. A significant drop of the filling pressures occurred which persisted for 6 to 8 hours.

Administration, Cutaneous↗