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Biomedical subjects

M Steiner

Publications and source records attributed to M Steiner.

At least 469 records · Page 26Linked to original sources
PubMed1979

[Influence of two prophylaxis programs on the gingival status of children].

Two groups of schoolchildren from the city of Zurich and the community of Wallisellen were compared for gingival health and disease by the Sulcus Bleeding Index. The children of Wallisellen who received more intensive prophylactic program than the Zurich schoolchildren showed better gingival health in every age group. More prophylactic education and more frequent instructions for Zurich schoolchildren are indicated.

Adolescent↗
PubMed1979

[Decrease in interdental bone atrophy, radiological survey; statistics from the years 1963-1976 from a Basel public dental clinic].

The material of this study consisted of 300 patients 16 to 39 years of age of the Public Dental Clinic of the City of Basle without destructive periodontal disease. The distance from the cementoenamel junction to the alveolar septum (DJS) was measured on bitewing radiographs at 8 surfaces of the lateral segment. On the radiographs made during the period 1963-1967, the average DJS ranged between 0.93 and 1.49 mm in the 5 age groups. Since 1964-1967, patients have routinely been given theoretical and repeated practical training in prevention of caries and periodontal disease. On the radiographs made during the period 1973-1976, the range of the averages was from 0.65 to 1.01 mm. The decrease of the DJS, 0.35 mm on average, was statistically significant in all 5 age groups.

Adolescent↗
PubMed1979

Behavioral toxicity. Neuroleptic-induced paradoxical behavioral toxicity in young borderline schizoprenics.

9 young borderline schizophrenics who developed an acute paradoxical behavioral toxicity as a reaction to the initiation of antipsychotic medication are described. The dynamics, the psychological issues as well as some possible psychopharmacological interactions are discussed. The risk of behavioral toxicity should not be overlooked or underestimated and the occurrence of this reaction must be carefully differentiated from other drug-induced reactions.

Adult↗
PubMed1979

Urinary 3-methoxy-4-hydroxyphenylglycol (MHPG) excretion in depression.

Twelve acute depressed patients were studied in the course of antidepressant treatment. Three-day-24-hour urine samples for 3-methoxy-4-hydroxy-phenylglycol (MHPG) were collected both before and after a five week treatment schedule. MHPG were estimated by spectrophotometry. Initial MHPG excretion did not reflect the severity of pretreatment depression and final MHPG showed no specific correlation with post-treatment improvement. No specific or uniform influence of different anti-depressant treatments or changes in MHPG was evident. Depressed patients with bipolar affective disorder tend to have initially lower MHPG levels than patients with unipolar depression. Urinary MHPG excretion measurements may prove not to be a useful index in the diagnosis and choice of treatment in patients suffering from primary depression.

Adult↗
PubMed1978

Sulfhydryls of platelet tubulin: their role in polymerization and colchicine binding.

Sulfhydryls and disulfides of platelet tubulin have been quantified, their accessibility and reactivity measured, and their role in polymerization and colchicine binding evaluated. Platelet tubulin isolated by two cycles of temperature-dependent polymerization--depolymerization was found to contain 12 free sulfhydryl groups per tubulin monomer all of which reacted rapidly with p-chloromercuribenzoate. One sulfhydryl was inaccessible to dithiobis(nitrobenzoic acid). Under anaerobic conditions of tubulin extraction, one intrachain disulfide bridge was found per tubulin monomer. Polymerization of tubulin reduced the number of sulfhydryls by one which were able to react with p-chloromercuribenzoate or dithiobis(nicotinic acid) but did not affect the disulfide bridge. Polymerizability of platelet tubulin was very sensitive to blocking of free sulfhydryl groups. Complete inhibition of microtubule assembly was obtained when the number of free sulfhydryls per tubulin was reduced by 3 but could be reversed by the addition of dithiothreitol. Colchicine binding, on the other hand, was only minimally influenced by blocking of sulfhydryls.

Blood Platelets↗
PubMed1978

Evaluation of a gingival inflammation test: gindex.

The Gindex test was compared with two gingival inflammation indices (GI and PBI) and with three plaque indices (SPI, thickness and extension index). There was no statistically significant correlation between the results of the Gindex test and the results of the other indices. When duplicate determinations of the same saliva sample were made with the Gindex test the results differed considerably. The Gindex test is considered to be inaccurate and of no value in the objective assessment of clinical inflammation of the gingiva.

Dental Plaque↗
PubMed1978

Cardiopulmonary resuscitation training in american dental schools and requirement for state licensure.

A questionnaire was sent to every American dental school and each state and regional testing agency, requesting information on the teaching of basic cardiopulmonary resuscitation (BCPR) and its inclusion in the requirements for state dental licensure. The data indicates that 81 percent of the schools teach a course in BCPR and the remaining 19 percent may do so in the future. Presently, 5 states require certification in BCPR for licensure and 17 states indicated they will require BCPR certification shortly.

Curriculum↗
PubMed1978

Solid-phase radioimmunoassay for morphine, with use of an affinity-purified morphine antibody.

Morphine antibody purified by affinity chromatography was used to develop a solid-phase radioimmunoassay for morphine in polystyrene tubes. The tubes are coated with an appropriate concentration of the purified antibody, rinsed three times with buffered saline, and stored at -15 degrees C. Using tritiated dihydromorphine, we determined competitive morphine binding by difference when the radioactivity in the assay supernates was measured after incubation (1 h, 37 degrees C). Five standard curves, with use of serum equivalents of morphine ranging from 0 to 6 mug/liter, were linear and had a mean correlation coefficient of 0.98. Uncer conditions of the assay, levorphanol was comparable to morphine in its inhibitory effect on binding of labeled dihydromorphine, whereas dextrorphan was essentially inactive. Morphine-3-glucuronide, a major metabolite, is 55-fold less inhibitory in terms of its capacity to displace the radiolabel. We believe that the sensitivity of the technique, coupled with the simplicity of nonseparatory sampling, renders the system suitable for rapid determination of morphine and related compounds in biological fluids.

Antibodies↗
PubMed1977

A psychosomatic triad in a bipolar patient.

A 56-year-old white male with a rare case of psychosomatic triad occurring during a single depressive episode is presented. The dynamics, course, and treatment are discussed. It is suggested that common psychosomatic mechanisms are interacting with the bipolar illness.

Asthma↗
PubMed1976

Effect of platelet age on adhesiveness to collagen and platelet surface charge.

Adhesion to collagen was investigated as a function of platelet age in rat platelets. Platelet adherence was measured using EDTA-containing platelet- rich plasma which was added to preparations of collagen fibers clamped between magnetic stirrers by recording changes in light transmission. The plot of light transmission versus logarithm of time was linear and allowed calculation of a slope factor which related to the rate of adherence. Neither the amount of collagen nor the platelet count were limiting in the test. Young platelet populations (less than or equal to 1 day old) were obtained during the recovery phase from immune induced thrombocytopenia. Old platelet populations were prepared by blocking thrombopoiesis with cyclophosphamide. Young platelets showed a moderate but statistically significant increase in adhesivity to collagen but old platelets did not differ significantly from randomly aged platelets in this function. The electrophoretic mobility of platelets was not affected by their age.

Animals↗