The use of the ambulatory setting for patient self-education.
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Biomedical subjects
Publications and source records attributed to M Stein.
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Aspirin idiosyncrasy is infrequently discussed in the dental literature. The severity of the case described illustrates the importance of complete familiarity with the syndrome. Because the patient who is sensitive to the drug may not volunteer this information, the dentist must include specific questions about asthma, nasal polyps, and adverse clinical reaction to aspirin in the initial interview of the patient. Suspicion of this idiosyncrasy will result in avoidance of aspirin; this may well prevent a life-threatening reaction. Acetaminophen is a safe alternative analgesic agent for such patients.
Attitudinal data obtained from interviewing random samples of women and men physicians in metropolitan Detroit indicated that women were generally more liberal and egalitarian than men. Older women were more liberal/egalitarian than older men while younger men were closer in attitudes to younger women. Within specialities, women and men physicians frequently held similar attitudinal scores; however, controlling for age, sex accounted for more variation than did specialty. A weighted combination of variables which together most significantly discriminated between age and sex subgroups pointed to a sensitivity dimension. This was stronger in the women; yet men demonstrating a similar sensitivity were found in almost every age and specialty grouping. Although younger men physicians are less conservative than older men physicians, both younger and older women physicians demonstrated strong liberalism/egalitarianism.
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Antigens present in leukemic sera and organ extracts, but absent from non-leukemic sera and tissues, were detected by examining their reactions with anti-microbial antisera by means of counter-immunoelectrophoresis. Out of 110 different antisera used, 12 antisera, those produced against Micropolyspora, Coccidioides, Salmonella, Mycoplasma, Mycobacterium simiae, Absidia, pseudorabies virus and adenovirus, proved to react regularly with the leukemic sera. Absorption studies point to an immunological specificity of these cross-antigenicities. Interpretations and implications of these discoveries are discussed in the paper.
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Data obtained from random samples of 87 women and 95 men physicians in the Detroit metropolitan area indicate that, at the time of surgery, 84% of the women and 96% of the men were engaged in medical work. Only 7% of the women were not working because of reasons related to the traditional female role. Fifty-nine percent of the women and 87% of the men had worked full-time since medical school graduation. Fifty-one percent of the women, compared to 39% of the men were in primary care specialties. Since medical graduation, women physicians spent 90% as much time in medical work as did the men, despite the fact that most of the women had full responsibility for homes and families.
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Experimental acute hypercarbia in dogs produced significant blood loss from the upper gastrointestinal tract, as well as from the small and large intestines. At necropsy, gross and microscopic examinations demonstrated necrotizing lesions resembled the postmortem ulcerations found in some patients with severe hypercarbia. Superior mesenteric arteriograms performed in four animals shortly after onset of hypercarbia showed abnormalities consistent with vasoconstriction. Vagal inhibition by atropine and correction of respiratior acidosis by TRIS buffer failed either to reduce the blood loss or to alter the pathologic lesions. Multiple studies of blood coagulation in the hypercarbic animals revealed no consistent changes when compared with eucarbic animals. In four animals treated with phenoxybenzamine during hypercarbia, blood loss and hemorrhagic gastrointestinal lesions were diminished, suggesting possible pathogenetic role of alpha-adrenergic stimulation. Although the mechanism is not proved, vasoconstriction secondary to adrenergic stimulation may play an important bleeding occurring with hypercarbia.
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A rare case of osteochondroma (osteocartilaginous exostosis) of the mandibular condyle is described; this represents the seventh documented case in the English language literature. Treatment consisted of transoral surgical resection which maintained condylar integrity. No maxillomandibular fixation was placed and the patient's mandibular function was undisturbed. Postoperatively, mandibular deviation was minimal.
Personal interview data obtained from 87 randomly selected women physicians in metropolitan Detroit indicates that productivity of women physicians has increased over that shown in previous studies. Eighty-four percent were engaged in medical work at the time of survey, 90% full-time. Only 7% were not working for reasons related to being a woman. Fifty-nine percent had worked continuously full-time since medical school graduation. Nearly half do not plan to retire from medical work. Fifty-eight percent are in private practice and 51% in primary care specialities; 54% are board certified. Direct patient care was listed as their main task by 86% of the women. Sixty-seven percent are married (43% to physicians). Although the 87 women physicians have responsibilities for households containing a total of nearly 300 people, almost one third of whom are children under 18 years old, their productivity is high.
It has been shown experimentally that psychosocial processes influence the susceptibility to some infections, to some neoplastic processes, and to some aspects of humoral and cell-mediated immune responses. These psychosocial effects may be related to hypothalamic activity. Reviewing the mechanisms that may be involved in the role of the hypothalamus in immune responses indicates that there is no single mediating factor. Various processes may participate, including the autonomic nervous system and neuroendocrine activity. The research reviewed has been limited primarily to a consideration of the effect of hypothalamic lesions on humoral immune responses. There is some evidence (45, 80) indicating that hypothalamic lesions also modify cell-mediated immune responses. Further research is required to evaluate the effect of the hypothalamus on cell-mediated immunity.
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When rat pulmonary tissues are processed as outlined in this paper, the type II cell's surfactant containing osmiophilic inclusion bodies possess a periodic substructure. This substructure consists of electron-opaque lamellae, 26 A in thickness alternating with 16 A wide electron-translucent zones.