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Biomedical subjects

M Staudacher

Publications and source records attributed to M Staudacher.

At least 55 records · Page 3Linked to original sources
PubMed1981

[Cardiac arrest following protamine sulphate administration (author's transl)].

This study presents the case history of a patient who suffered from recurrent pulmonary embolism, despite heparinisation, after a car accident and who died during preparation for caval ligature. We feel that the protamine sulphate given for neutralization of the heparin effect played an important role, since no signs of massive pulmonary embolism were found at autopsy. Protamine sulphate is known to possess a significant cardiovascular depressive action. On the basis of a survey of the literature the possible potentiation of circulatory insufficiency by changed haemodynamics following pulmonary embolism, induction of anaesthesia, and protamine sulphate is discussed. Proposals for improved management of such case are made.

Acute Disease↗
PubMed1979

[Extra-anatomical bypass grafting in high-risk patients (author's transl)].

Extra-anatomical grafting (axillo-femoral and femoro-femoral bypass) seems to present a possibility of saving the lower limbs from amputation in high-risk patients with severe decompensation from arterial occlusive diseases of the legs. A case description is given of 20 patients, in whom 21 bypass procedures were carried out. The results with axillo-femoral bypass proved satisfactory and this method of intervention can be recommended as an emergency operation in high-risk patients.

Aged↗
PubMed1979

[Femoro-crural reconstruction in preference to amputation (author's transl)].

22 cases of arterial occlusion below the branching of the popliteal artery and 1 case of traumatic subtotal amputation of the calf were revascularized by autogenous femoro-crural vein bypasses. All patients had pain at rest and/or gangrene. So far, with an average bypass patency of 15 months in two of three equal parts of the operated legs, the decision to try reconstruction instead to amputate has met with successful results. The operative technique is described in detail and the speical problems of this group of patients and the particular difficulties of this technically sophisticated bypass procedure are discussed.

Adult↗
PubMed1975

Lyophilized veins studied by scanning electron microscopy.

Human saphenous veins were studied by scanning electron microscopy. The intention was to analyze the suitability of lyophilized homologous veins for homografting when no autologous venous material is available for replacement of obstructed arterial segments. Cross-sectioned specimens revealed the intimal layer of the venous wall to be compactly structured, while the median and external parts were found to be loosely organized and contained numerous cavities. The luminal surface coat displayed the typical aspects of an intact endothelium with occasional fine deposits of fibrin. Defects of the inner layer were only rarely observed, and are caused when the endothelium was stuck to the PVC catheter prior to lyophilization. From a morphological point of view, lyophilized veins seem to be sutiable for replacement of arterial segments. Based on our findings suggestions are made for optimal preparation of the venous material.

Freeze Drying↗