[Influence of glucocorticoids and ACTH administration on the outcome of experimental adrenal transplants].
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Biomedical subjects
Publications and source records attributed to M Srougi.
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The efficiency of cavernospongiosum shunt in the management of priapism was evaluated in 10 patients. Technical details such as the "Z" perineal incision and the opening followed by closure of the contralateral corpus cavernosum, at the time of corpora evacuation, can improve the local exposure and permits a more complete drainage of the corpus cavernosum, but did not improve our results when they were compared with other techniques for treatment of priapism. Penile flaccidity and preservation of sexual potency occurred in 6 (60%) and 5 (50%) patients, respectively, and no surgical complications were observed. Immediate penile flaccidity and regaining of physiologic erection were, however, not complete even in the successfully treated patients. The cavernospongiosum shunt does not seem to represent the definitive form of treating priapism. New knowledge about mechanisms involved in priapism has to be obtained, in order to improve the approach and the prognosis of this disabling condition.
New tools for the diagnosis of adrenal diseases and the development of successful techniques to treat patients with bilateral tumors of the kidney have increased the number of procedures involving removal of both adrenals. Offering to these patients an adrenal autograft represents more than a superfluous medical exercise, since a successful outcome of the graft will relieve them of the burdens and risks of long-term postoperative steroid replacement therapy. The aim of this review is to bring to mind the possibility of autografting adrenal glands in some clinical situations and to emphasize some points that could be relevant in obtaining successful results. The available data justify clinical trials with the procedure.
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Treatment of penile fracture, due to the low number of cases, still lacks adequate documentation. The authors present two cases of such pathology, which were treated conservatively, and presented penile deformities in the late follow up. Both conservative and surgical management are discussed; since surgery in these cases has low mortality and clinical treatment can be followed by various sequelae, the authors favour the former, stressing that it is mandatory in cases with urinary obstruction, progressive infiltration of cutaneous laceration.
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