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Biomedical subjects

M Spector

Publications and source records attributed to M Spector.

90 records · Page 5Linked to original sources
PubMed1970

Stepping test.

Explore the source record for details and available documents.

Gait↗
PubMed1969

Atherosclerotic plaque: x-ray diffraction investigation.

Human atherosclerotic plaque material continuotusly maintained in an aqueous environment has been subjected to examination by x-ray diffraction. The first diffraction pattern from single crystals of human biological apatite was obtained from the plaque material of a freshly excised plaque when it was equilibrated with its aqueous environment. As the plaque material dried, the discrete spots characteristic of single crystal diffraction disappeared, leaving only the powder pattern of apatite.

Apatites↗
PubMedDate not supplied

Quantitative characterization of cells at the interface of long-term implants of selected polymers.

Comprehensive understanding of the relationship between biologic response and biomaterial characteristic requires quantitative evaluation of the cells at the interface of the material and descriptions of ultrastructural features of these cells. The purpose of this study was to qualitatively and quantitatively characterize the long term in vivo tissue and cellular response to two polymeric materials presently employed in the fabrication of surgical implants. Ultrahigh molecular weight polyethylene (PE) and polysulfone (PSF) particles were implanted subcutaneously into rats for 100-118 weeks. Specimens were embedded in paraffin and ERL embedding medium in preparation for light and transmission electron microscopy. Percentage of the particle surface covered by various cell types was determined using a computer interactive image analysis system. PE and PSF particles were sequestered within a subcutaneous fibrous capsule. Cell types present included macrophages, fibroblasts and giant cells characteristic of a foreign body granuloma. Statistical comparison of the percent particle surface covered by each cell type revealed no significant difference between PSF and PE. However, surface texture appeared to influence the tissue response. TEM confirmed the identity of the cells at the interface and consistently revealed a layer of amorphous extracellular substance including cell debris on the material surface. Results evidence the tissue compatibility of PE and PSF and indicate no significant difference in the tissue response to these polymers.

Animals↗
PubMedDate not supplied

Electronystagmographic findings in central nervous system disease.

A helpful central sign on electronystagmography with eyes closed is hyper-excitability on a caloric test. Another sign is consistent nystagmus in the presence of normal calorics. With eyes open, calibration overshoot, gaze nystagmus, pendulum tracking, failure of tracking a pendulum were by far the most common central abnormality in the experience of the author.

Brain Neoplasms↗