OBJECTIVE: To describe the radiological findings of long-standing pulmonary epithelioid hemangioendothelioma. MATERIALS AND METHODS: Serial radiography and CT, including high-resolution CT scans, were performed in two patients. RESULTS: The tumor has remained radiographically stationary for 10 and 20 years, respectively. On CT, both patients showed multiple calcified pulmonary nodules, up to 1 cm in size with a perivascular distribution. Interstitial involvement was seen in one case. CONCLUSION: Calcification and perivascular location of the tumoral nodules were characteristic CT findings in our cases.

Female↗

PubMedDate not supplied

Focal segmental glomerular sclerosis in two patients with Addison's disease: any more than fortuitous development of glomerular disease?

Adjustment of the mineralocorticoid activity under substitution therapy is of primary importance in Addison's disease. We report the clinical and biological conditions of 2 patients with Addison's disease who developed nephrotic proteinuria during their deficient mineralocorticoid state. Renal biopsy was performed and the specimens processed using conventional histochemistry, Congo red staining, and indirect immunofluorescence. The renal biopsy specimens showed focal segmental glomerular sclerosis and nodular deposits of IgM and C3. Negative for Congo red staining. Serum complement, circulating immune complexes, and anti-DNA and hepatitis B and C and human immunodeficiency virus antibodies were all normal or negative. Absence of vesicoureteral reflux was assessed by X-ray studies. Our observations suggest that deficiency in mineralocorticoid substitution therapy inducing a status of hyperreninemia could play a role in the development of focal segmental glomerulosclerosis in patients with Addison's disease.

Addison Disease↗

PubMedDate not supplied

Fine needle aspiration of myofibroblastoma of the breast in a man. A report of two cases.

The cytopathologic features of fine needle aspiration biopsy of two myofibroblastomas of the breast in men are described. The cytologic findings consisted of monomorphic spindle cells with ovoid, grooved nuclei, isolated or in clusters, with an ill-defined, short fascicular pattern and abundant acellular, myxoid-appearing material. Atypical features were absent. No epithelial elements were present. We emphasize the value of aspiration cytology in association with clinical and mammographic data to establish a definitive diagnosis of this uncommon entity. This benign tumor should be considered in pure spindle cell, nontypical fine needle aspiration biopsy specimens of breast masses with sharp demarcation from the surrounding tissue, especially in men.

Adult↗

PubMedDate not supplied

[Testicular and epididymal malacoplakia. Presentation of a case and review of the literature].

A case of testicular malacoplakia and epididymis in a 62 year old man is presented. A literature review is made (only 6 cases describing epididymal malacoplakia have been reported), commenting on the clinical, diagnostic, anatomopathological, pathogenic and therapeutic aspects of malacoplakia.

Epididymis↗

PubMedDate not supplied

[Secondary bladder amyloidosis. A rare cause of hematuria].

Secondary vesical amyloidosis is an uncommon pathology and few cases are described in the literature. A suddenly appearing hematuria resistant to treatment in a patient with a diagnosis of systemic amyloidosis is usually the initial sign that guides us to its diagnosis. We present a case of vesical amyloidosis in a patient with systemic amyloidosis secondary to a Rheumatoid Arthritis of length evolution, and which was diagnosed as a result of a pattern of massive incoercible hematuria.

Amyloidosis↗

PubMedDate not supplied

[Ruptured mycotic aneurysm of the femoral artery].

After several commentaries about mycotic aneurysms related to drug addicts, author exposes the case of a young man attached to heroin, presenting a ruptured femoral mycotic aneurysm, surgically treated. Surgery in these cases is commented on.

Adult↗

PubMedDate not supplied

[Calcified kidney masses. Study of 23 cases].

We consider the presence of calcifications in a series of 107 renal masses by means of simple X-ray, echography and CAT, in which 23 cases (21.4%) were found. The most effective exploration for revealing them was CAT (in 13% of the cases, the only one). We found a relative higher frequency of calcification in the benign masses (31%) than in the neoplastic ones (17%). In the latter we found no differences in survival as compared with the non-calcified ones. No pattern of calcification proved characteristic of benignity or of neoplasia. The variety of malignant renal mass most often calcified was the papillary hypernephroma (57.1%).

Adenocarcinoma↗

PubMedDate not supplied

[Bladder lavage cytology in the diagnosis and follow-up of superficial bladder cancer].

Classical mictional cytology (MC) has a series of widely recognized limitations for the diagnosis and follow-up of surface vesical carcinoma (SVC). A prospective study was conducted in 171 patients with suspected signs and symptoms or a background of SVC using cystoscopy, MC and vesical lavage cytology (LC). Overall sensitivity was 98.8%, 45.4% and 66.6% respectively. LC showed a significant difference (p < 0.05) when compared to MC in suspected disease with no SVC background, and follow-up with endovesical prophylaxis.

Adult↗

PubMedDate not supplied

Value and limitations of cytologic criteria for the diagnosis of hepatocellular carcinoma by fine needle aspiration biopsy.

In order to further evaluate the utility of fine needle aspiration biopsy (FNAB) cytology for the diagnosis of hepatocellular carcinoma (HCC), we analyzed 39 cytologic features in a series of 102 FNABs from HCC and compared them with 28 FNABs from nonneoplastic conditions. Thirteen features were significantly associated with HCC; from them a stepwise logistic regression analysis selected the three most predictive: irregular arrangement, irregular chromatin pattern and uniformly smaller cytoplasm, the last two found only in HCC. Using different specific combinations of significant cytologic features, the highest sensitivity obtained was 84.3%, with 100% specificity. Sixteen HCC cases could not be diagnosed specifically using the criteria defined in this study, probably due to their well-differentiated nature or to sampling error. Although the use of additional techniques, such as cell block preparations, would improve the results in well-differentiated tumors, we recommend basing the early diagnosis of small HCC on a multidisciplinary approach.

Biopsy, Needle↗

PubMedDate not supplied

[Eosinophilic cystitis. Report of 4 cases].

OBJECTIVE: The etiopathogenesis, clinical features, diagnosis and treatment of eosinophilic cystitis are discussed. METHODS/RESULTS: 4 cases of eosinophilic cystitis are described. Patient follow-up ranged from 4 to 6.5 years. All patients are currently asymptomatic. Except for one patient who required hospitalization on several occasions due to hematuria secondary to cystitis, the remaining patients had an exceptional episode. CONCLUSIONS: Eosinophilic cystitis is an inflammatory condition whose etiopathogenesis remains to be elucidated. Its natural history is usually unpredictable and treatment is rarely effective. Eosinophilic cystitis has been associated with other allergic disorders and has been reported in patients with BPH and carcinoma of the bladder.

Aged↗