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Biomedical subjects

M Snyder

Publications and source records attributed to M Snyder.

At least 253 records · Page 14Linked to original sources
PubMedDate not supplied

Primary care management of common dermatologic disorders in women. Pharmacologic considerations.

This article describes the clinical management of dermatologic disorders most commonly encountered in the primary care setting. The common presenting clinical signs and symptoms are reviewed, and the initial laboratory tests that may establish the diagnosis are recommended. Pharmacologic and nonpharmacologic treatments are reviewed. Diagnosis and management of disorders of the sebaceous and apocrine glands, disorders of the hair and pigmentation, fungal, viral, and bacterial infections, dermatitis, and infestations are discussed. A review of the care of skin burns and wounds is included as well as the diagnosis and management of urticaria.

Antiparasitic Agents↗
PubMedDate not supplied

Barriers to progress in urinary incontinence: achieving quality assessments.

Urinary incontinence is a major care problem in nursing homes. Despite legislation aimed at decreasing its incidence, minimal progress has been made to achieve this goal. Obtaining an accurate assessment about the level and pattern of incontinence will assist caregivers in developing plans to reduce it. This article identifies barriers the authors have encountered in obtaining accurate records in a research project and strategies implemented to overcome these barriers.

Aged↗
PubMedDate not supplied

Bent DNA at a yeast autonomously replicating sequence.

DNA fragments that show retarded electrophoretic mobility through polyacrylamide gels have been found in both prokaryotes and eukaryotes. In the case of kinetoplast DNA, evidence has been presented that the DNA is curved or 'bent'. Bent DNA has previously been found at the lambda and simian virus 40 (SV40) DNA replication origins. Here we show the existence of bent DNA at a yeast autonomously replicating sequence (ARS1), a putative replication origin. The bent DNA has been localized to a 40-55 base pair (bp) segment and contains six (A)3-5 stretches (that is, six poly(A) stretches, three to five nucleotides in length) phased approximately every 10.5 bp. This region contains a DNA binding site for a yeast protein factor. This site lies at the 3' end of the TRP1 gene, in a region devoid of nucleosomes, and is positioned 80 bp away from the ARS consensus sequence; removal of this region impairs ARS function in vivo. The bent DNA may be involved in transcription termination or the prevention of nucleosome assembly in this region.

Base Sequence↗
PubMedDate not supplied

A glider swing intervention for people with dementia.

The soothing, repetitive movement of rocking and swinging is well known to anyone who has enjoyed a porch swing or rocking chair. Positive effects of rocking have been reported. However, investigations on its effect in people with dementia are limited. The purposes of this quasi-experimental, repeated-measures design study were to measure the effects of a glider swing on emotions, relaxation, and aggressive behaviors in a group of nursing home residents with dementia (n = 30). Data were obtained during a 5-day baseline phase, a 10-day intervention phase, and a 5-day posttreatment phase. Subjects were placed on the glider for 20 minutes each day during the intervention phase. The results of the study indicate that the glider intervention significantly improved emotions and relaxation. The most noted changes were found after 10 minutes of swinging. However, no differences were found in aggressive behaviors.

Adult↗
PubMedDate not supplied

Clinical use of tai chi in elderly populations.

Tai chi, a type of low-intensity exercise, has received growing attention in both eastern and western cultures, especially its use with the most rapidly increasing segment of the population-elders. Previous research findings further supported the idea that tai chi is appropriate for elderly populations and helps promote their well-being. In this article, the beneficial effects of tai chi for elders are summarized, resources to increase awareness about the exercise are provided, and ways to promote tai chi in elderly populations are suggested.

Aged↗
PubMedDate not supplied

Impact of triiodothyronine on the survival of high-risk patients undergoing open heart surgery.

Experimental and clinical studies have shown the beneficial effects of triiodothyronine (T3) following myocardial revascularization on cardiopulmonary bypass (CPB). In this study, open-label T3 was administered to 68 high-risk patients undergoing open heart surgery. The New Jersey Risk Assessment was used to calculate the preoperative estimated surgical mortality. A loading dose of T3 was administered: (a) at release of the aortic cross-clamp, (b) whenever the patient became CPB dependent, (c) if the patient exhibited low cardiac output after discontinuing CPB and (d) as pretreatment before initiating CPB. All therapeutic modalities were followed by a continuous T3 infusion. Following T3 therapy, CPB was discontinued in all patients. Based upon discriminant analysis, a total of 26 deaths were expected from the entire group, but only 7 patients died, therefore, the observed mortality was reduced by 72% (p < 0.007). The use of T3 had a major impact on reducing surgical mortality, and may be advocated as a new therapeutic modality in patients with high estimated mortality undergoing open heart surgery.

Adult↗
PubMedDate not supplied

Challenges of implementing intervention research in persons with dementia: example of a glider swing intervention.

Intervention studies for persons with dementia present many challenges. This article describes challenges encountered in conducting a glider swing intervention study for persons with dementia and the strategies used to manage the problems encountered. The overall purpose of a quasi-experimental study was to explore the effects of a glider swing intervention on emotions, relaxation, and aggressive behaviors in nursing home residents with dementia. Suggestions for investigators conducting intervention studies for persons with dementia are provided.

Adult↗
PubMedDate not supplied

Monitoring progress after lung transplantation from home-patient adherence.

A paperless electronic spirometer/diary instrument has been employed in a home monitoring programme for lung and heart-lung transplant patients at the University of Minnesota. The monitoring programme is part of a long term study to develop a system which will detect the earliest signs of developing rejection or infection in the transplanted organs. It is based on patient daily self-measurements of standard spirometry, vital signs, and symptoms recorded at home and transmitted weekly to the study data center over the telephone using a modern built into the instrument. This report summarizes adherence behaviour for 41 subjects enrolled in the study over a 12 month period. The number of subjects from whom home data has been received each week was used to measure adherence at the subject level. The number of records received each week measured adherence at the daily recording level. A data record consists of a daily set of spirometry, vital signs, and symptom values from a given subject. Approximately 82% of subjects transmitted records each week, over the 52 week review period. There was an average of 4.5 records received each week from each subject. Transmitted records had missing vital sign or symptom items in less than 2% of cases, spirometry data was always present. This evaluation showed than lung transplant recipients are willing and able to use a home-monitoring instrument, and that basic spirometry, data entry, and data transmission can be performed satisfactorily.

Adolescent↗
PubMedDate not supplied

Stressors, coping mechanisms, and perceived health in persons with epilepsy.

Knowledge is lacking about the nature of stressors experienced by persons with epilepsy and the strategies used to cope with these stressors. This study explored epilepsy-specific stressors, coping strategies used, level of trait anxiety, and perception of health in 107 adults who had had epilepsy for 1 year or longer. 'Need to take medications regularly' and 'Uncertainty about when a seizure will occur' were the stressors subjects ranked highest. 'Try to maintain some control over the situation', 'Hope things will get better', and 'Think through different ways to solve the problem' were the top coping strategies used. Persons who perceived their health as better used more problem-oriented strategies than did those who rated their health as poor. The mean level of trait anxiety was 42.1, which is higher than that for a normal population. Continued studies are needed to more clearly identify stressors experienced at various times in the trajectory of epilepsy and the precise coping strategies used for specific stressors.

Adaptation, Psychological↗
PubMedDate not supplied

Critical thinking: a foundation for consumer-focused care.

Both providers and recipients of health care services are now focusing attention on not only what is provided but also how services are provided. The goal is consumer satisfaction, with pressure on the provider of services to meet customer demands. This shift in focus challenges the knowledge and skills of nurses, and their ability to solve problems in collaboration with their customers. To provide consumer-focused care, nurses will need to develop critical thinking skills that utilize logical/analytical and intuitive/creative approaches to solving problems. Critical thinking skills that integrate these two approaches will provide practitioners expertise in flexible, individualized, and situation-specific problem solving. Nursing staff who are able to focus on the consumer will be better prepared to meet the demands of today's competitive health care market. The challenge facing educators is to prepare nurses with a foundation from which to provide this care.

Humans↗
PubMedDate not supplied

Congenital anophthalmos. Ultrasonographic diagnosis of congenital anophthalmos.

Congenital anophthalmos must be differentiated from "clinical anophthalmos" where blepharophimosis renders examination of the contents of the orbit impossible. Ultrasonographic examination of these orbits can be performed for documentation of the total absence of cyst-like ocular structures without the need for examination under anesthesia and surgical exploration. Two cases of true anophthalmos have recently been seen by us and the diagnosis confirmed ultrasonographically.

Adult↗