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Biomedical subjects

M Snyder

Publications and source records attributed to M Snyder.

At least 217 records · Page 12Linked to original sources
PubMed1979

Inability to demonstrate hydroxylation of tyrosine by murine melanoma "tyrosinase" (L-DOPA oxidase), using the tritiated water assay technique.

Validity of the tritiated water assay technique for tyrosine hydroxylase activity as a qualitative method was demonstrated with mushroom tyrosinase. Using this method, isolated murine melanoma "tyrosinase" (L-dopa oxidase) showed no tyrosine hydroxylase activity. This finding supports previous studies in our laboratory which used a variety of histochemical and biochemical methods. The nonenzymatic production of tritiated water caused by tritium exchange with hydrogen peroxide complicates the use of the tritiated water assay technique with crude systems, since hydrogen peroxide is generated by a variety of oxidase reactions. For this reason, previous studies using the tritiated water assay technique with crude systems are ambiguous.

Animals↗
PubMed1978

Chip fracture through the superior articular facet with compressive cervical radiculopathy.

Four patients with cervical radiculopathy secondary to a chip fracture through the superior articular facet have been treated in the past 2 years. These small-element fractures may occasionally pass unrecognized. Although oblique X-rays are helpful, lateral tomography has provided the most precise detail. The pathological process is a compressive radiculopathy, explicable on the basis of the foraminal anatomy. The authors feel myelography is not essential. The preferred surgical approach is posterior: the results have been excellent.

Adult↗
PubMed1977

Intracranial hemorrhage associated with anticoagulation therapy.

Nine patients with intracranial hemorrhage associated with long-term anticoagulation therapy were evaluated at the Wadsworth Veterans Administration Hospital over a 30-month period. The relationships of the hemorrhage to other variables, both in this series and in the review of the literature, are analyzed. The most common site of the intracranial hemorrhage was the subdural space. No direct correlation between the presence of arterial hypertension or prothrombin activity and intracranial hemorrhage existed. The outcome was favorable in six of the patients, four of whom had a subdural hematoma.

Aged↗