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Biomedical subjects

M Sironi

Publications and source records attributed to M Sironi.

190 records · Page 11Linked to original sources
PubMedDate not supplied

Immunoperoxidase study of cytologic smears in oral pemphigus.

A case is reported in which the oral mucosa was involved by pemphigus vulgaris; the lesions were studied by the taking of cytologic smears. The use of an immunoperoxidase stain for IgG on the smears, some of which were already stained by the Papanicolaou technique, gave a positive reaction in the intercellular spaces and on the cell membranes and provided a precise diagnosis of the lesions.

Adult↗
PubMedDate not supplied

Undifferentiated granulocytic sarcoma: a case with epidural onset preceding acute promyelocytic leukemia.

This study reports a case of granulocytic sarcoma that developed in the epidural zone 25 days before clinical evidence of an acute promyelocytic leukemia. The case presented the diagnostic difficulties that are common to all aleukemic granulocytic sarcomas. Moreover, it highlights the very rare association between granulocytic sarcoma and acute promyelocytic leukemia, which is far from being explained.

Adult↗
PubMedDate not supplied

Ganglioglioma: a clinical and pathological study of 12 cases.

We report the clinico-pathological and immunohistochemical findings of 12 cases of gangliogloma that were diagnosed at Legnano Civil Hospital over a period of 10 years. The patients' age at presentation ranged from 2-69 years with a mean duration of symptoms equal to 52 months. Seizures were the most common presenting symptoms. These tumors, mainly located in the temporal lobe (5/10), displayed in 10 cases a low density appearance at CT scan. Histologically the tumors were composed of neoplastic ganglion cells mixed together with a glial component. All but one of the tumors were surgically treated: complete removal was accomplished in 8 cases and incomplete in 3 cases; 1 case was an incidental autopsy finding. Radiotherapy was administered in the incompletely removed cases. The mean follow-up period was 40.8 months, with 3 patients deceased. Our findings support the notion that ganglioglioma is a slow-growing relatively benign tumor of young adults, ubiquitous in the central nervous system with a non-specific CT scan appearance and varied histological morphology, in which immunochemical stains will confirm the diagnosis and could provide a prognostic marker.

Adolescent↗