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Biomedical subjects

M Singh

Publications and source records attributed to M Singh.

At least 811 records · Page 45Linked to original sources
PubMed1990

Neurobehavioral hemispheric preferences: a case of sexual dimorphism.

Ninety subjects (47 females and 43 males) with age ranging from 17 to 25 completed a neurobehavioral inventory of hemispheric preference. The inventory (Wagner & Wells, 1985) consists of 12 items, each of which has 4 statements that relate to four different functions of the two hemispheres namely: (a) Left-logical (b) Left-verbal (c) Right-manipulative/spatial and (d) Right-creative. The results indicated an overall preference for verbal-logical tasks. This preference pattern was more pronounced in males than in the female subjects. Also, the female subjects exhibited greater preference for creative tasks (activities), whereas the males showed preference for verbal tasks. These results suggests that proficiency and preference may not necessarily follow the similar pattern.

Adolescent↗
PubMed1990

HIV-I antibodies in health and disease.

Antibodies to human immune deficiency (HIV) virus were studied in 2000 individuals including cases of non-Hodgkin's lymphoma, systemic lupus erythematosus (SLE), leprosy, chronic renal failure on haemodialysis and patients attending STD clinics. A group of blood donors was also screened, ELISA kits provided by Wellcome Diagnostics were used. Results indicate that the ELISA values were far above the cut off figure in all except in a couple where the husband who had stayed in Uganda for several years, and had features of full blown AIDS died 4 months after the diagnosis. The spouse contacted AIDS within a relatively short incubation period and died within 6 months of diagnosis. The North Indian population thus appears to be free of this virus so far. This observation will be an important lead mark in the future epidemiology of HIV infection in India.

Adult↗
PubMed1990

Complications of intermittent peritoneal dialysis.

Two hundred and ninety three sessions of intermittent peritoneal dialysis were carried in 158 cases of renal failure between 1984 and 1987. The complications encountered during the procedure were grouped as mechanical in 29 (17.9%), circulatory in 26 (15%), neurologic in 21 (13.4%) and biochemical in 54 (34.1%) cases. Unexplained respiratory arrest with spontaneous recovery occurred in 2, infections in 5 and miscellaneous complications in 19 (12%) cases. Bradycardia and cardiac standstill were observed in one patient. Most of the complications were managed uneventfully. There was no mortality.

Acute Kidney Injury↗
PubMed1990

Evaluation of steam therapy in acute lower respiratory tract infections: a pilot study.

In a prospective controlled evaluation of steam therapy, in severe acute lower respiratory tract infection (ALRI) requiring hospitalization, 16 cases of bronchiolitis and 20 cases of pneumonia were assigned alternately to receive steam therapy in a cloth tent (Study Group); others served as controls. Respiratory status was assessed at the time of admission and subsequently at 6 hourly interval for 48 hours. No advantage of steam therapy could be identified in children with pneumonia. Bronchiolitis patients on steam therapy, as compared to the controls, showed a significant decrease in respiratory distress within first 24 hours after hospitalization and took significantly shorter time for recovery from the distress. The study patients also showed a tendency for rapid improvement in hypoxemia. Further critically controlled studies with a larger sample size are warranted.

Acute Disease↗
PubMed1990

Experimental test-object study of electronically collimated SPECT.

The imaging performance of a prototype electronically collimated single-photon emission computed tomography (SPECT) camera comprising a unique 4 x 4 germanium detector backed by an uncollimated scintillation camera has been evaluated. Three-dimensional images of cylindrical test-objects containing either 99mTc (140 keV) or 137Cs (662 keV) are reported. Electronically collimated counts were acquired from the objects rotated to 20 or 40 angular positions in front of the germanium detector to simulate a cylindrical scanning system. For comparison, mechanically collimated data were also acquired from the test-objects. The SPECT images show a slightly better resolution for mechanical over electronical collimation (1.3 +/- 0.25 cm mechanical, 1.5 +/- 0.25 cm electronical at 140 keV; 1.5 +/- 0.25 cm mechanical, 1.7 +/- 0.25 cm electronical at 662 keV). The equi-resolution sensitivity, however, was deduced to be approximately an order of magnitude higher with electronic collimation to image a head-sized object using 99mTc. In addition, the sensitivity gain increases with increasing energy, suggesting the unique potential of electronic collimation in high-energy SPECT.

Electronics↗
PubMed1990

Polycythemia in the newborn: do asymptomatic babies need exchange transfusion?

A total of 2288 infants were screened for hematocrit over a period of 15 months. Polycythemia was diagnosed in 27 cases (1.2%). Preterm and term babies had more or less equal risk to develop polycythemia (1.5% and 1.1% respectively) while postterm infants had at least three times increased risk (3.4%) when compared to their term counterparts. Large-for-dates (LFDs) and small-for-dates (SFDs) infants had increased risk of manifesting polycythemia which was nearly four times (2.2%) and twenty-five times (13.2%) respectively, as compared to appropriate-for-dates (AFDs) babies (0.5%). About one-third of polycythemic infants had one or more symptoms. The most common symptoms observed was jitteriness (25.9%) followed by respiratory distress (14.8%) and lethargy (11.1%). The mean (+/- SD) hematocrit of symptomatic newborns (76.0 +/- 4.04) was found to be significantly higher (p less than 0.001) as compared to asymptomatic babies (70.84 +/- 2.73). Partial exchange transfusion with plasma was performed in all the symptomatic cases within 8 hours of onset of symptoms. No such intervention was performed in asymptomatic cases. On neurodevelopment follow-up, the development indices (MDI and PDI) of both asymptomatic and symptomatic cases were found to be comparable.

Growth↗
PubMed1990

Cord blood red-cell enzymes and reduced glutathione in Indian neonates, normal and with pathologic jaundice.

Red-cell enzymes and reduced glutathione (GSH) were assayed on cord blood in 307 Indian neonates. On follow-up, 20 of them developed pathologic jaundice. Of these, six had red-cell enzyme/GSH deficiency, seven had associated non-enzymatic causes of jaundice, and in the remaining seven the cause could not be diagnosed. In 41 other neonates, there was enzyme/GSH deficiency without pathologic jaundice. The degree of enzyme deficiency had no relation with jaundice. Red-cell enzyme/GSH deficiency state in neonates was associated with pathologic jaundice more frequently (six of 47; 12.8%) than in the absence of such deficiency (14 of 260; 5.4%). None of the jaundiced patients had very high levels of bilirubin nor needed exchange blood transfusion. There was no reduction in haemoglobin level in the enzyme/GSH deficient group with jaundice in comparison with non-deficient jaundiced neonates or normal subjects. The incidence of red-cell enzyme/GSH deficiency appears to be high in Indian neonates; however, the majority of them do not precipitate pathologic jaundice.

Analysis of Variance↗