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Biomedical subjects

M Shirai

Publications and source records attributed to M Shirai.

At least 343 records · Page 19Linked to original sources

Treatment of organic impotence by implantation of silicone penile prosthesis.

To help bolster penile tension mechanically, we have tried implantation of silicone penile prostheses varying in type. Our simple and apparently successful procedures for organic impotence with the implantation of intrapenile silicone prostheses may well deserve recommendation in view of spinal impairment therapeutically categorized irreparable.

Erectile Dysfunction↗

The effect of visual sexual stimulation on urinary excretion of adrenaline and noradrenaline in impotent patients.

In 15 impotent patients, the effect of visual sexual stimulation was evaluated by measuring their urinary levels of adrenaline and noradrenaline, before and after stimulation. Both adrenaline and noradrenaline increased in the urine over the base levels in response to the visual sexual stimulation. The average increases were 1.5 times for adrenaline, and 1.4 times for noradrenaline. There was an evident correlation between the degree of sexual excitation and the excretion of adrenaline and noradrenaline into urine.

Adult↗

Impetus to transferring non-motile sperm in the seminiferous tubules into the epididymis.

Effect of intratesticular pressure was examined on non-motile sperms in the testis whether they move toward the epididymis when it is raised. The head portion of the epididymis of the dog was cut apart at the proximal portion to the testis fully exposing the lumen of the epididymis. The electric stimulation of perivascular nerves of the spermatic cord caused spermatozoa to flow out onto the incision site at 5 min. The number of them increased progressively, almost innumerable at 15 min. These results support the view that the elevated intratesticular pressure by electric stimulation surely works to transfer non-motile sperm in the seminiferous tubules into the epididymis.

Animals↗

FSH, LH and testosterone levels in human seminal plasma.

Testosterone levels in the seminal plasma of 5 normal males, and 30 male sterility patients were measured by radioimmunoassay. In 9 random cases, seminal plasma levels of FSH and LH were determined by radioimmunoassay. The average level of seminal plasma testosterone for the normal males was 72 +/- ng/100 ml, higher than that of the patients: 52 +/- 41 ng/100 ml. The average levels of FSH and LH in the seminal plasma of the 9 random cases were 4.4 +/- 2.0 mIU/ml and 35.4 +/- 5.4 mlU/ml, respectively.

Follicle Stimulating Hormone↗

Changes in plasma levels of LH, FSH and testosterone following the administration of synthetic luteinizing hormone-releasing hormone to cryptorchid patients.

The levels of LH, FSH and testosterone of three adult groups consisting of normal subjects, unilateral and bilateral cryptorcids were compared before and after LH-RH loading. It was found that both groups of cryptorchid had comparatively high plasma base line levels for both LH and FSH, particularly high in the bilateral group; and both groups responded to LH-RH loading. This indicates that their hypothalamo-hypophyseal systems were probably functioning normally. The plasma base line levels of testosterone were higher in unilateral cryptorchids than in the control group, and lowest in the bilateral cryptorchid group. But the reaction of testosterone levels to LH-RH loading was generally poor in both groups of cryptorchids, suggesting that, in cryptorchid cases, unilateral and bilateral, the capacity of the testicle to secrete testosterone is generally depressed, freeing central suppression. This probably accounts for the high values of plasma lh and FSH observed in such patients.

Adolescent↗

Diagnostic discrimination between organic and functional impotence by radioisotope penogram with 99mTcO4.

Since the half-life of 99mTc is only 6.04 hr, its massive dosing for an elevation of diagnostic accuracy is possible with reduced radiation exposure to the body. On 11 impotent cases, radioisotope penogram was performed with 99mTcO4. The results indicate that the penogram curves obtained are satisfactorily favorable for diagnostic discrimination between organic impotence and functional impotence.

Adult↗