Search PubMed⌕ Search

Biomedical subjects

M Shipley

Publications and source records attributed to M Shipley.

78 records · Page 5Linked to original sources

Controlled trial of homoeopathic treatment of osteoarthritis.

In a double-blind, placebo-controlled crossover study to compare the homoeopathic remedy Rhus tox. 6X with fenoprofen in osteoarthritis of the hip and knee, fenoprofen was shown to have beneficial analgesic and anti-inflammatory effects which differed significantly from those of placebo. The effects of Rhus tox. 6X and placebo did not differ significantly. Patient preference was for fenoprofen. Side-effects were not severe but were seen more frequently with fenoprofen. Similar results were seen in all patients regardless of whether they had been referred to and assessed by a homoeopathic physician or a rheumatologist.

Adult↗

Employment grade and coronary heart disease in British civil servants.

The relationship between grade of employment, coronary risk factors, and coronary heart disease (CHD) mortality has been investigated in a longitudinal study of 17 530 civil servants working in London. After seven and a half years of follow-up there was a clear inverse relationship between grade of employment and CHD mortality. Men in the lowest grade (messengers) had 3.6 times the CHD mortality of men in the highest employment grade (administrators). Men in the lower employment grades were shorter, heavier for their height, had higher blood pressure, higher plasma glucose, smoked more, and reported less leisure-time physical activity than men in the higher grades. Yet when allowance was made for the influence on mortality of all of these factors plus plasma cholesterol, the inverse association between grade of employment and CHD mortality was still strong. It is concluded that the higher CHD mortality experienced by working class men, which is present also in national statistics, can be only partly explained by the established coronary risk factors.

Adult↗

[Activation of T lymphocytes in the blood and joints of patients with rheumatoid polyarthritis].

The proportion of T Lymphocytes with receptors for interleukin 2 is increased in the blood, the synovial fluid and, in particular, the synovial membrane in rheumatoid arthritis. However, there is no correlation between the percentage in blood and the percentage in the joints. The helper T lymphocytes are proportionately more activated than the suppressor T lymphocytes.

Antigens, Surface↗