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Biomedical subjects

M Shepherd

Publications and source records attributed to M Shepherd.

At least 127 records · Page 7Linked to original sources

Psychotropic drugs and taxonomic systems.

Attempts to underpin the classification of psychiatric drugs in biological and clinical terms are discussed with reference to their value and limitations. The current need for a multiplative, heuristic taxonomy is suggested.

Psychotropic Drugs↗

Mediastinal lymph node biopsy in sarcoidosis.

Mediastinoscopy, in the skilled hands of a thoracic surgeon has proved to be a safe, cosmetically accepted procedure with negligible complications. It has yielded a high rate of diagnostic lymph node tissue; overall greater than 82% among patients with sarcoidosis, including patients presenting with pulmonary mottling only or with a normal chest radiograph. Among patients with lymphatic tuberculosis it enabled the isolation of human M. tuberculosis following culture of the lymph node removed on Löwenstein-Jensen medium in greater than 79% of cases. A precise histological diagnosis was obtained in all 14 patients presenting with hilar and/or paratracheal lymphadenopathy attributable to malignant disease.

Adult↗

[The epidemiological approach to depression (author's transl)].

The epidemiological method is indispensable to the clinical investigator, the practising clinician and the public health worker. In the field of mood disorders epidemiological inquiry has been hampered by the subjective nature of the phenomena under study, the problems of assessment and diagnosis, observer bias and the unrepresentative nature of small population samples. Nontheless, it is argued that the difficulties are similar to those encountered elsewhere in medicine and examples are given of epidemiological contributions to an understanding of depression.

Adolescent↗