Search PubMed⌕ Search

Biomedical subjects

M Shani

Publications and source records attributed to M Shani.

At least 109 records · Page 6Linked to original sources
PubMed1976

The effect of phenobarbital on patients with Dubin-Johnson syndrome.

11 patients with jaundice of Dubin-Johnson type were treated for 2 weeks with phenobarbital. Serum bilirubin diminished and hepatic clearance of sulfobromophthalein was variably enhanced; other measures of hepatic function were not significantly changed during therapy.

Adolescent↗
PubMed1975

Acute myocardial infarction. Prognostic value of white blood cell count and blood glucose level.

Data obtained in the course of a nationwide study of patients with first acute myocardial infarction (AMI) demonstrated substantially higher hospital mortality among patients with leukocytosis or elevated blood glucose levels, or both. It is suggested that the combination of these two measurements could be used as a handy diagnostic indicator in the evaluation of some AMI patients and as a criterion for the patients' immediate disposition to a coronary care unit, rather than to a general ward.

Acute Disease↗
PubMed1975

Reduction of hospital mortality from acute myocardial infarction by anticoagulant therapy.

A nationwide study of all 2330 patients hospitalized for a first definite acute myocardial infarction in Israel during a one-year period revealed a significantly lower 21-day mortality rate of patients treated by anticoagulants: 8.3 versus 27.3 per cent in those not receiving such therapy (p less than 0.0001). Out of the 22 hospitals studied, the effect was present in 18, absent in two, and not assessable in two. There was a highly significant inverse correlation between the proportion of patients receiving anticoagulant therapy in each hospital and the total 21-day mortality from infarction in that institution (r equals 0.57; less than 0.01). The superior survival of patients on anticoagulant therapy did not seem related to differences in age, sex, disease severity, site of infarction, diagnostic criteria or type of hospital. Despite the obvious limitations of retrospective studies the data justify a re-evaluation of the approach to the problem by further investigative effort.

Acute Disease↗
PubMed1975

Esophageal cancer in Israel: selected clinical and epidemiological aspects.

Records of all patients diagnosed as having carcinoma of the esophagus in Israel between 1960 and 1966 were reviewed. The mean annual incidence was 2.3/100,000, with a male/female ratio of 1.6:1. Incidence was higher among the Asian-born segment of the population below 60 years of age. The most frequent localization was in the middle third of the esophagus, followed by the lower third. More than two thirds of the patients were considered unsuitable for surgery. Overall 5-year survival was 5.8%.

Adenocarcinoma↗
PubMed1975

RNAs of simian virus 40 in productively infected monkey cells: kinetics of formation and decay in enucleate cells.

We demonstrate here the usefulness of cytochalasin B enucleate cells for the study of the metabolism of cytoplasmic mRNA and for determining its half-life in animal cells. Simian virus 40 infected monkey cells in which the RNA had been labeled with [3H]uridine were enucleated, and the decay of the two prominent RNAs of simian virus 40, the 19S and 16S species, was measured by analysis on sucrose gradients. The results of these experiments, together with kinetic analysis of nuclear and cytoplasmic viral RNA, indicate a precursor-product relationship between the 19S and 16S cytoplasmic viral RNA species, which decay by first-order kinetics with a mean half-life of about 3 hr and 6 hr, respectively.

Animals↗
PubMed1975

Some epidemiologic aspects of acute myocardial infarction in Israel.

A nationwide study of acute myocardial infarction in Israel was carried out during a one-year period. There were 2,504 new and 968 repeated attacks. Annual incidence rate of first attacks was 0.9 per 1,000 (1.3 in men and 0.5 in women). Incidence was highest among the European born in both sexes. But, while the pattern of the native born men was similar to that of those born in Europe, it approached the incidence of the Asian-African born in women. The sex ratio was relatively higher in those ethnic groups where male incidence was relatively higher and vice versa. Length of residence in the country had little effect on the incidence rates.

Acute Disease↗
PubMed1975

Factors affecting immediate mortality of patients with acute myocardial infarction: a nationwide study.

The hospital mortality was evaluated for 21 days in all patients with a first attack of acute myocardial infarction (AMI) in Israel. Total mortality was 21.1 percent. The following factors were associated with relatively better prognoses: age, young; sex, male; marital status, married; ethnic origin, European; site, subendocardial; history of smoking, and, to a certain degree, hypertension; low levels of white blood cells, blood sugar, serum transaminase and cholesterol; and anticoagulant therapy.

Acute Disease↗