The structures and stereochemistry of majdine and isomaydine.
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Alkaloids↗
Biomedical subjects
M Shamma
Publications and source records attributed to M Shamma.
[On the identity of vellosine and refractine].
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Alkaloids↗
The structures of deserpideine and raujemidine.
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The stereochemistry of the pentacyclic oxindole alkaloids.
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The problem of the 1,2,9,10-tetraoxygenated aporphines and the structure of the quaternary aporphine from Fagara tinguassoiba.
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[Stereochemistry of oxindole alkaloids].
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Thalictrum alkaloids. II. Thalidastine.
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Rates of methiodide formation and the stereochemistry of the ethyl side chain of Iboga type alkaloids.
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Alkaloids↗
The alkaloids of Delphinium cashmirianum.
Dephinium cashmirianum Royle (Ranunculaceae) has yielded the new base cashmiradelphine (12), together with the known alkaloids anthranoyllycoctonine (9), lycaconitine (15), avadharidine (17), lappaconitine (4), and N-deacetyllappaconitine (7). Pyridinium chlorochromate oxidation of lycoctonine furnished the new aldehyde lycoctonal (11). The arrhythmogenic and heart rate effects of several of these diterpenoidal alkaloids have been measured on the isolated guinea atria. Lappaconitine was arrhythmogenic at 10(-4)M concentrations. But in contrast to the reference drug aconitine, lappaconitine did not increase the heart rate. In anesthetized rabbits injected with lappaconitine, N-deacetyllappaconitine, and lappaconine up to 1 mg/kg, cardiac arrhythmia was quickly observed. Even up to 5 mg/kg, the other substances were non-arrhythmogenic.
Alkaloids↗
Thalidine, a new isopavine alkaloid from Thalictrum dioicum.
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