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Biomedical subjects

M Shahabpour

Publications and source records attributed to M Shahabpour.

At least 37 records · Page 2Linked to original sources
PubMed1993

Osteomalacia in a patient with anorexia nervosa.

A 32-year-old patient with anorexia nervosa since adolescence was admitted because of diffuse bone pain, increasing during the 2 preceding winters. She had a special aversion to dairy products and all forms of dietary fat. Low normal serum calcium and very low calciuria were noted, with a highly elevated bone fraction of alkaline phosphatase, and severe hypovitaminosis D and B12. Apart from a recent spontaneous fracture of the clavicle, Looser lines and pseudofractures were noted in a finger, fibula and malleolus. In particular, magnetic resonance imaging of the knee showed additional evidence of a pseudofracture in the femur, and medullary changes were found. Evidence for secondary hyperparathyroidism was described. Apart from the well known occurrence of osteoporosis, our case shows that osteomalacia may exceptionally occur in anorexia nervosa.

Adult↗
PubMed1992

[MRI of the wrist joint].

Due to the development of new surface coils and the use of thin slices, MRI has become an essential diagnostic tool in wrist pathology. After several technical considerations, the authors describe the normal MRI appearance of the various anatomical structures of the wrist, particularly the triangular fibrocartilaginous complex of the wrist and the elements of the carpal tunnel. They review the principal indications for MRI: chronic diseases such as carpal tunnel syndrome and traumatic ligamentous and cartilaginous lesions. The bone marrow lesions detected in the presence of occult fractures and osteonecrosis of the lunate or scaphoid are then briefly considered. The diagnostic criteria of median nerve compression (carpal tunnel syndrome) include morphological and signal changes in the nerve, abnormal palmar convexity of the flexor retinaculum and signs of tenosynovitis of the intracarpal flexor tendons. However, in practice, MRI is only useful when there is disagreement between the clinical and EMG findings and in postoperative recurrences, in which case it may reveal insufficient section of the retinaculum or the presence of exuberant postoperative fibrosis responsible for persistent nerve compression. Traumatic tears of the triangular fibrocartilage are characterised by a linear high signal intensity image (on T1 and T2 weighted sequences), usually situated in the periphery of the articular disk. Degenerative lesions tend to be central, within the disk and are frequently observed after the age of 40 years.

Carpal Bones↗
PubMed1992

Imaging and differential diagnosis of synovial sarcoma.

Synovial sarcoma is an uncommon malignant tumor, most frequent in the lower extremity, predominantly in young males. The authors review the clinical history, the different radiographic manifestations and MR appearance of the entity. The MR findings cannot be considered specific for synovial sarcoma. A heterogeneous septated mass located close to a joint, a tendon or a bursa is most indicative of the tumor. The radiographic features of a soft tissue mass with associated calcifications and bony erosions in the lower extremity should suggest a synovial sarcoma. The most likely differential diagnoses are discussed.

Adult↗
PubMed1992

Magnetic resonance imaging (MRI) of the ankle and hindfoot.

While Magnetic Resonance Imaging (MRI) has become a routine diagnostic method to deal with pathology of the knee, little has been published about foot and ankle lesions. This is probably due to the anatomic complexity of bone and ligamentous structures of these small joints, necessitating the use of very thin slices from various orientation planes (orthogonal and oblique planes). A special technique is needed allowing a 3-dimensional (3D) analysis, using inframillimetric slices and more sophisticated equipment than for 2-dimensional (2D) MRI (high fields with good homogeneity, specialized image processors...). An initial potential indication of the method is the precise diagnosis of lateral ligamentous components in severe sprains. MRI may determine if surgical therapy is needed. The ligamentous components are reconstructed along their specific planes thanks to the 3D method. Furthermore, assessment of the ligamentous damage is also possible in chronic ankle instability (elongation, fibrotic appearance...). Thanks to the multiplanar approach, associated lesions of articular cartilage can be revealed in ankle sprains. The high sensitivity of MRI in slight modifications of medullary bone allows the early diagnosis of "occult" fractures (not seen on conventional radiographs), osteonecrosis, osteochondrosis and reflex sympathetic dystrophy syndrome. Finally, MRI easily displays all ankle and foot tendons and fascia and is particularly helpful in depicting partial tears and postoperative complications.

Adult↗
PubMed1992

[Dissection of the sub-astragalar ligaments and magnetic resonance imaging].

The aim of this study is to find the different ligamentous structures in the subtalar region through dissection and to compare them with images obtained on MRI. MRI allows visualization of the different ligamentous structures with greater precision than with computerized tomography. This investigation should permit a more precise diagnosis of injuries often poorly understood in this region.

Humans↗
PubMed1991

[Carpal tunnel syndrome. Comparative studies of pre- and postoperative magnetic resonance and electromyography].

A comparative wrist study was conducted in a total of 36 subjects: 20 normal volunteers and 16 patients with diagnosed carpal tunnel syndrome. 1.5 Tesla MR was used with a cylindrical extremity coll. The authors reviewed the anatomy of the wrist in the normal subjects. The accuracy of MR diagnostic criteria for carpal tunnel syndrome was assessed in comparison with EMG results and surgical findings. The authors conclude that MRI has proved to be reliable and useful in the diagnostic work up of carpal tunnel syndrome. Its main indication would be in cases of negative or doubtful EMG.

Adult↗
PubMed1991

[Immunohistology of bullous autoimmune skin diseases].

Autoimmune bullous dermatoses undertake frequently oropharyngeal mucous membranes and the skin surface, either in succession or simultaneously. Actual observation technics by photon and electron microscopy, by immunofluorescence and immunohistochemistry (with specific antibodies) have allowed to differentiate more particularly pemphigus, bullous pemphigoid, cicatricial pemphigoid, acquired bullous epidermolysis, all autoimmune bullous affections.

Autoimmune Diseases↗
PubMed1990

Chondral lesions of the patella evaluated with computed tomography, magnetic resonance imaging, and arthroscopy.

In a small series of cadaver knees, experimentally created lesions of the patellar cartilage were compared using contrast computed tomography (CT) and magnetic resonance (MR) imaging. Contrast CT was able to recognize only 50% of the lesions smaller than 3-mm diameter at the first attempt, and none of the lesions of 0.8 mm. MR imaging detected all the lesions, even those as small as 0.8 mm, without use of contrast material. Simultaneously, a prospective clinical study comparing MR diagnoses of chondral lesions with arthroscopic findings was initiated in a series of 54 knees. This clinical study revealed that, concerning patellar chondral lesions, the accuracy of MR imaging compared with arthroscopy (the gold standard) was 81.5%. The sensitivity was 100%, but the specificity only 50% due to the false positives. Reexamination of the MR records enabled us to refine the MR diagnosis and to propose a staging of the chondral lesions. The high rate of false-positive results in our series can be explained by the hypothesis that MR imaging can possibly detect very early lesions, which appear as abnormalities in the deep cartilage layers.

Adult↗
PubMed1990

[Magnetic resonance imaging in knee injuries].

Of all the diagnostic imaging techniques for the injured knee, Magnetic Resonance Imaging (MRI) has been shown the most worthwhile. Indications for standard X rays, arthrography and ultrasonography are briefly reviewed. Advantages of MRI, the technical aspects and the sequences used are explained. After a short description of the signals of all the common anatomic components of the knee, we describe MR findings in meniscal pathology, tenoligamentous lesions and cartilage and bone injuries.

Humans↗
PubMed1989

CT arthrography and MRI of the patella.

The importance of CT scanning in the diagnosis of patello-femoral disorders is reviewed and illustrated. CT double-contrast technique is compared to Magnetic Resonance Imaging (MRI) using both clinical examples and a cadaver study. The authors demonstrate the superiority of MRI to CT in detecting retropatellar cartilage lesions.

Adult↗
PubMed1989

Gaucher disease.

Explore the source record for details and available documents.

Femur Head Necrosis↗
PubMed1989

Osteoblastoma of the patella. Case report and review of the literature.

Benign osteoblastoma is a rare tumor; the majority of lesions occur in the spine, femur, and tibia. Osteoblastoma in the patella is so rare that it seems not to have been reported previously in more than one case. A 29-year-old man with a sports injury, who failed to respond to conservative treatment over a prolonged period of time, was later found to have an osteoblastoma of the patella.

Adult↗
PubMedDate not supplied

SLAP lesions: a retrospective multicenter study.

A retrospective analysis of 530 glenohumeral arthroscopies performed by three independent Belgian arthroscopists revealed the presence of 32 SLAP lesions, which represents an incidence of 6%. Since this is exactly the same percentage as found by Snyder et al., we report our data in this article. We classified 23 of the SLAP lesions using Snyder's classification, 7 needed the additional classification of Maffet et al., and 2 lesions were considered to be anatomic variations; 53% of the lesions were of type II. Concerning the mechanism of injury, we found comparable percentages of traction (22%) and compression (28%) injury as reported by Snyder, but also a high number (25%) of overhead sports activities as described by Andrews et al. Associated lesions were in close accordance with Snyder's data, but a relatively low incidence of rotator cuff injuries (10%) was present. Comparison of treatment regimens showed that the same percentage of lesions (34%) was fixed arthroscopically in both series. Only SLAP II, IV, and V lesions must be considered as unstable and in need of fixation. We confirm that patients' complaints and clinical symptoms are vague and inconsistent. Imaging, using computed tomographic arthrography or magnetic resonance, was performed in a minority of cases. Advantages and pitfalls of both techniques are discussed. Anatomic variations causing an extra-large sublabral hole are shown, and we warn about potential diagnostic and therapeutic errors in these cases.

Adolescent↗
PubMedDate not supplied

The accuracy of three-dimensional magnetic resonance imaging in the diagnosis of ruptures of the lateral ligaments of the ankle.

In a prospective study, the diagnostic accuracy of three-dimensional magnetic resonance imaging in the evaluation of ruptures of the lateral ligaments of the ankle was determined by comparing three-dimensional magnetic resonance findings with operative findings. In a series of 18 consecutive cases of acute significant inversion trauma to the ankle, a three-dimensional fast imaging with steady-state precession pulse sequence (3D FISP) was performed. The study included only those cases in which views showed a difference in talar tilt of 15 degrees or more, and a difference in anteroposterior drawer of 10 mm or more between the imaged and the normal ankle. All ankles were scheduled for surgical exploration. Compared with operative findings, the sensitivity, specificity, and accuracy of 3D FISP imaging were, respectively, 100%, 50%, and 94.4% for ruptures of the anterior talofibular ligament and 91.7%, 100%, and 94.4% for ruptures of the calcaneofibular ligament. We believe that 3D FISP magnetic resonance imaging is a noninvasive, fast, and very accurate diagnostic aid to operative planning for double ligament tears in younger competitive athletes.

Acute Disease↗
PubMedDate not supplied

MR imaging findings of bone marrow changes in patients with cystic fibrosis.

The purpose of this work was to evaluate bone marrow abnormalities in the lower limbs of patients with cystic fibrosis by means of MR imaging. Eight patients with cystic fibrosis ranging in age from 16 to 35 years (average age 25.1 years) were evaluated with MR imaging of the lower extremities. T1 weighted spin echo sequences were obtained in all patients. Pelvis, femora and tibia were imaged in the coronal plane whereas the feet were imaged in the sagittal plane. The studies were independently evaluated by two musculoskeletal radiologists. The images were not mixed with disease-free images, but the readers were completely unaware of clinical data. Distribution of haematopoietic and fatty marrow was graded on a 5-point scale. In five patients, both observers considered marrow distribution as probably or definitely abnormal relative to their age. Although our findings are very preliminary, our investigation suggests that cystic fibrosis may be added to the list of disorders in which bone marrow abnormalities may be observed.

Adult↗
PubMedDate not supplied

Imaging of semimembranosus bursitis: MR findings in three patients and anatomical study.

We report on three patients with posteromedial knee pain related to semimembranosus bursitis. The semimembranosus bursa has a typical location and morphology around the central tendon of the semimembranosus muscle. These characteristics are demonstrated in patients and by dissection of the tendon and bursa in an embalmed knee specimen.

Adult↗