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Biomedical subjects

M Severin

Publications and source records attributed to M Severin.

46 records · Page 3Linked to original sources
PubMed1979

[Patients on dialysis--late fundus controls (author's transl)].

In 102 patients on dialysis for renal failure late fundus controls have been done to studie the response of retinal vessels to blood pressure reduction. In 52 patients follow up studies were possible. Only 4 patients showed reversible changes of the vessels, in 4 other patients changes increased. In the majority of the patients hypertensive vascular changes (stage I or II) remained unchanged. Young age and deep diastolic pressure seems to be necessary for normalization of the fundus vessels. Vessel changes did not improve if the diastolic pressure was 90--100 mmHg and more.

Adult↗
PubMed1978

[Corneal changes in patients on dialysis for renal failure (author's transl)].

The corneas of 100 patients on dialysis for renal failure were observed. In 52 patients follow up studies were possible. 55 patients demonstrated limbal changes. On slit lamp biomicroscopy these changes showed to be similar to the white limbus girdle described by Vogt. Small limbal biopsies from five patients on dialysis were studies histopathologically and compared to biopsies from three patients with normal renal function. Only patients on dialysis showed senile elastosis and three of them epithelial and subepithelial hyaline deposits. Calcium deposition was the same in both groups.

Adolescent↗
PubMed1977

[Perforating keratoplasty in the presence of considerable changes of the anterior segment of the eye (author's transl)].

A report is given on 44 patients with penetrating keratoplasty in severe damage of the anterior eye. The first group consisted of 31 patients with acute, deep inflammatory processes of the cornea, threatened by perforation or with perforation and severe iritis. The second group of 13 patients had had perforating injury with corneal scar, broad anterior synechiae and lens remnants. In group 1 55% had visual function between 0.3 and 1.0; 35.5% showed no improvement, 10% got worse. In group 2 only 5 patients had visual improvement from 0.3-1.0. In 3 patients there was a negative outcome. The indication for corneal graft in these groups and the right moment of operation are discussed. We tried to compare our own results with other statistics.

Corneal Opacity↗
PubMed1976

[Present status of locating intraocular foreign bodies (author's transl)].

The different procedures used today to locate intraocular foreign bodies are discussed. The x-ray procedure is not adequate for splinters near the wall, questionable double perforations and foreign bodies which cannot be demonstrated radiographically. Complementary methods of examination such as transillumination, electroacustic location, ultrasonics and direct radio-optic controls must be used. Advantages and limitations of these individual locating procedures are discussed. Intensive transillumination with glass-fiber diaphanoscope is particularly important for splinters in the anterior section of the eyeball near the wall. Ultrasonics cannot be replaced by other methods for foreign bodies in the posterior section of the eyeball which do not produce shadows, demonstration of the relationship of the foreign body to pathologic intraocular structures and the measurement of the length of the eyeball. At the University Ophthalmic Hospital in Cologne, direct radio-optic controls are conducted with a stereo-x-ray image amplitier, a stereoscopic image that gives.

Eye Foreign Bodies↗
PubMed1975

[Quantitative determinaton of glycerides by densitometry (author's transl)].

After determination of charring conditions and the measurement by densitometry of lipids separated by thin-layer chromatography, a statistical analysis was performed to determine the significance of the results. Calibration curves were studied and response factors calculated for some saturated and unsaturated triglycerides.

Chromatography, Thin Layer↗
PubMed1975

[Eye changes in familial juvenile nephronophthisis (author's transl)].

5 patients from three families with confirmed diagnoses of nephronophthisis and eye changes are described. All patients showed along with relatively slight decreased function changes in the pigment epithelium and the choroid. In three of these patients the ERG was pathologically reduced. Contrary to the known observations from the literature our patients showed no typical signs of congenital retinal Leber's amaurosis. The observed changes in the sclera reflect the gravity of the illness. With dialysis treatment the progress of the disease could in two patients be arrested for 4 years.

Adult↗
PubMedDate not supplied

Dexamethasone bovine pharmacokinetics.

Dexamethasone phosphate (DXM-PHO) is an ester which is quickly hydrolysed by the bovine and the dexamethasone (DXM) plasma half-life was 5.16 h. It has been demonstrated that 54 h after DXM-PHO injection, DXM concentrations were lower than 0.1 mg/ml. Tritiated dexamethasone was also administered twice to an another young bull for metabolite investigation. The elapsed time required to recover, in plasma, half of the radioactivity injected was 8.8 h. Radioactivity recovery in the urine reached 36.4% and 22.6% for the first and the second injections respectively.

Animals↗