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Biomedical subjects

M Seremet

Publications and source records attributed to M Seremet.

At least 19 recordsLinked to original sources

Clinical research of dental erosion.

On the base of performed clinical studies of a possible appearance of dental erosion in patients, it can be concluded as follows: 1) Out of 710 treated patients, in 62 is found the appearance of erosive changes of dental tissues. 2) Erosive changes were more prevalent in patients in the third age group, more often in male than in female. 3) Patients with erosive changes are with distinctive gastrointestinal disorders, they used the hard toothbrush, soft food, and in most of them is noticed the appearance of psychic disorders with the aggressive behaving. 4) Studies have shown the justification and the need to continue them by multidisciplined approach in a higher number of patients, a longer period, in order for better discovering the aetiology of erosive changes of dental hard tissues.

Adolescent

[Morphologic changes in the pulp and surrounding structures of the teeth in irradiated animals].

Several animals of the same breed (11 swine-white Landrace) were used in the research. Irradiation was made by radiation from the linear accelerator with lethal doses (3,68-4, 48 Gy). The changes on incisors and molars in the perished animals were observed as well as the changes on the surrounding structures of teeth. In the examined histological incisions of the dental pulp, paradontium, alveolar part of the bone and gingival part of the mucose of the oral cavity in the animals were found extensive confluent bleeding, dilatation of blood vessels with expressive edema of blood vessels intima. The endothelium showed the signs of edema, prominence toward the lumen or desquamation in the lumen. There were shallow defects in the gingival mucosa due to the necrosis and desquamation top-cover epithelium. The described changes fit into the findings of a large number of researches who accent hemorrhagic diathesis with petechial ecchymotic and confluent bleedings in many organs and tissues.

Animals

[Histologic picture of dental pulp in dogs treated with ZnOOK paste].

The activity of zinc-oxide paste on histologic changes of the pulp was examined while the indirect capping of the exposed dog tooth pulp was performed. The results showed that the histologic changes observed in dog tooth pulp were accompanied with hyperaemia and blood vessel dilatation then with the pulp oedema, slight disorder of odontoblast palisade and the presence of the traces of occurrence of tertiary dentin.

Animals

Prognostic value of some parameters of cellular immunity in breast cancer patients.

In 45 histologically verified breast cancer patients the cell-mediated immune responses were tested prior to surgical therapy. The cell immunity was assessed by the percentage of T and active T-lymphocytes and by measuring the lymphocyte reactivity to phytohemagglutin (PHA) and concanavalin A (Con A). Disease-free interval was longer and the mortality after 3, 5 and 8-year follow-up significantly lower in the group of patients with the normal number of T and active T-lymphocytes than in the group of patients with the lower number of those cells. The proliferative response of lymphocytes to Con A and PHA assessed in allogeneic and autologous serum also seemed to be a useful prognostic parameter. The survival was significantly longer in the group of patients with a normal lymphocyte reactivity to those mitogens than in the non-reactive group.

Breast Neoplasms

[Rotaviruses--causes of minor epidemics of diarrheal diseases in the neonatal department of the Pediatric Clinic in Sarajevo].

A rotavirus epidemic took place at the above mentioned department (8. V 1987 until 19. VI 1987). During that period, 36 newborn infants were treated for rotaviral symptoms and they all had their stools checked for rotaviruses or their antigen. Rotaviruses were found by 17 patients (47.2%). As a lab method we used immunoelectrophoresis. 20 patient of the overall number of 36 were boys and 16 were girls. Stool samples showed rotaviruses in 9 boys (45%) and 8 girls (50%). The age of patients was 3 to 34 days. After 1-14 days all children were well.

Bosnia and Herzegovina

[Comparison of the immunoenzyme test (ELISA) with other methods in the detection of rheumatoid factor].

IgM rheumatoid factor was detected, beside ELISA test, by Waaler-Rose, Latex agglutination and indirect immunofluorescent test. 107 patients hospitalized in the Clinic for heart diseases and rheumatism, as well as 50 healthy subjects were examined. In the first group were 50 patients with RA, 30 patients with other rheumatic diseases and 27 with nonrheumatic diseases. According to our results there was no significant difference between sensitivity of ELISA test and other laboratory tests used. ELISA test was positive in 94% of cases of RA, 20% in other rheumatic diseases and only in one case (3,7%) of a nonrheumatic disease. Compared with the control group in which there was no specific reaction, Waaler-Rose and immunofluorescent testing showed a nonspecific reaction in 2% and Latex test in 4% of all cases. Although ELISA test was not significantly sensitive as compared with other laboratory methods, according to our results, it has high reproducibility, specificity and precision (it is measured in international units/mL serum), and it allows following of the concentration of rheumatoid factor. Besides, ELISA test can be done on 100 specimen of blood within 6 hours and the results are known the same day.

Arthritis, Rheumatoid