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Biomedical subjects

M Seidel

Publications and source records attributed to M Seidel.

At least 55 records · Page 3Linked to original sources

[Polygraphic therapy control in Gilles de la Tourette syndrome--a case report].

In a female patient with Gilles-de-la Tourette syndrome (GTS) the clinical improvement during drug therapy of haloperidol and clomipramine was proved with the help of a polygraphic method (simultaneous recording of different electrophysiological and vegetative parameters). Before intensifying therapy symptoms of vegetative irritation, motoric discharge patterns with high amplitude in correlation with movements and permanent activity with low amplitude even in a state of external motoric rest were found. After intensifying therapy vegetative stabilization and ceasing of any electrical activity in the EMG could be demonstrated. It is concluded that the effects of therapy in GTS may be checked and quantified by means of polygraphic methods.

Adult↗

[Carl Westphal--a progressive university teacher of neurology and psychiatry in the 19th century].

Carl Westphal (1833-1890) is described on the basis of his theoretical considerations concerning the teaching of psychiatry and neurology and his influence on the contents and organization of teaching in these fields at the then Charité as a university teacher with progressive pedagogic and didactic aims and methods. His other scientific work shows that C. Westphal was a worthy heir and like-minded successor to W. Griesinger (1817-1868).

Germany↗

[Treatment trials with hemofiltration/hemodialysis in pernicious catatonia].

Two juvenile patients affected for the first time with pernicious catatonia were treated repeatedly with combined hemofiltration and hemodialysis. During the first two or three sessions, the distinct psychopathological improvement only persisted during the session itself and in a lesser degree during the following hours. It was only after further treatments that the therapy effect lasted longer and passed over into a continuous remission tendency. The findings might support a toxin hypothesis (in a broad sense) with respect to the genesis of catatonia and encourage a continuation of the studies.

Adolescent↗

[The status of extracorporeal detoxication procedures as a therapy method in schizophrenia].

The literature on the problem of extracorporeal detoxication in chronic schizophrenia was critically studied. For the statistically considered 132 cases of chronic schizophrenia without uraemia treated with haemodialysis, haemoperfusion and haemofiltration which are published in the literature (including 12 own cases) it was found that 38 per cent are considered as improved. The insufficient comparability of the examination methods and the want of clearness with respect to the specific therapy influence (placebo effect, etc.) leave the question open whether these are in fact efficient methods of treatment for some cases of chronic schizophrenia. A final decision on this requires continued, methodically more strictly controlled, and above all standardised examinations. The results obtained until now make efforts in this direction appear reasonable.

Adolescent↗

[Use of a mechanical variant of the Pauli test and the influence of several subjective and situational testing conditions].

Comparative examinations of the paper and pencil form and a mechanical variation (using a performance testing unit) of Pauli's performance test, in which a total of 100 students were included, showed differences in the specific requirements of the two variants and in the performance rating of the test subjects. Consequently, their mutual substitution appears unjustifiable. It was not possible for effects of a number of situational test conditions upon performance results to be demonstrated for this test sample. Hypothesized relationships between the Pauli test performance, on the one hand, and proficiency motivation, attainments, and variational motivation, on the other, could be verified in part of the cases only.

Adult↗

[Blood clotting and thrombocyte function in reversible hemorrhagic shock].

In experiments on 12 mongrel dogs, serving as models of reversible hemorrhagic shock, the influence on blood clotting and thrombocyte function was studied. Initial hypercoagulability, observed already after introduction of anesthesia, and multiplying of pathological aggregation stages dissociated from decreased number of thrombocytes suggest a considerable influence of the proceeding of reversible hemorrhagic shock on the clotting system. It is concluded that the initial hypercoagulability is not causally related to the changes of platelet function, which represent a starting mechanism for the arising of consumptive reaction in protracted and irreversible shock.

Animals↗