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Biomedical subjects

M Schroll

Publications and source records attributed to M Schroll.

168 records · Page 10Linked to original sources
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Predictors of five-year functional ability in a longitudinal survey of men and women aged 75 to 80. The 1914-population in Glostrup, Denmark.

Data from a longitudinal study of aging-a Danish substudy within a Nordic comparative longitudinal Research on Ageing study (NORA)-is presented. The goal is to highlight easily measured factors, that are relevant to prevention and postponement of disability in the elderly. In a population-based, representative sample, the objectives were: to describe five-year outcome regarding death and functional ability to age 75 to 80, as well as individual changes in muscle strength, physical performance in simple function tests and self-reported physical activity, and relate "risk markers" to five-year outcome. Baseline values were obtained in 405 participants in the 1989-survey of the 1914-cohort in Copenhagen County. The 307 survivors were invited for the survey of 80-year olds in 1995. Outcome was measured as death, non-participation, decline, stability or improvement in two measures of mobility function (tiredness and dependency). Between ages 75 and 80, 24% died, 12% did not participate in the follow-up, 23% became tired performing mobility functions, 20% did not change but 21% became less tired; 19% became more dependent, 44% remained stable and only 2% improved in relation to dependency on help in mobility functions. "Stability" in mobility functions was related to ability to mount stairs, walking speed, mood and physical activity. Number of chronic diseases and low pulmonary function were only related to mobility in men. Among people who improved their function, many had rather low baseline-values, suggesting regression to the mean. Multiple logistic regression was conducted. The follow-up survey found that female participants were more physically active at baseline than non-participants. Five-year mortality was independently related to physical activity (RR = 0.41), pulmonary function in men (RR = 0.45/l increase) and muscle strength in women (RR = 0.65/N/kg increase). Dependency at follow-up in men was related to low physical activity at baseline (RR = 4.14), disability to mount a 50-cm step (RR = 4.07), two or more chronic diseases (RR = 3.36) and, only marginally significant, knee extension strength. In women only low physical activity was predictive (RR = 4.32). From baseline to follow-up, 34% of the population had reduced their physical activities. Knee extension strength was reduced from 6.0 to 4.4 N/kg in men, and from 4.2 to 3.3 N/kg in women. In the stair-mounting test, 44% could only attain one or more 10 cm steps lower than at baseline. A dose-response-relationship of declining muscle mass to functional limitations was observed in men and women at the age of 75 as well as the age of 80.

Activities of Daily Living↗
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Changes in bicycle ergometer test performance and survival in men and women from 50 to 60 and from 70 to 80 years of age: two longitudinal studies in the Glostrup (Denmark) population.

BACKGROUND: During the aging process longitudinal changes for sustained work in humans are poorly understood. Only a few longitudinal follow-up studies have been published thus far, and most of them have been based on highly selected groups, such as physical education teachers or senior athletes. OBJECTIVE AND METHODS: On the basis of random samples of a general population, the purpose of this study was to analyze changes in bicycle test performance in two longitudinal designs: a 10-year follow-up period from 50 to 60 years of age, using a submaximal test protocol, and another 10-year follow-up period from 70 to 80 years of age, using indirect voluntary maximal tests. In addition, the preventive value of the bicycle test results for survival at different age levels was analyzed. The subjects in the first part of the study were members of a random sample of originally 514 men and 461 women living in the Glostrup area, close to Copenhagen, Denmark, in 1964. Of these, 367 men (71.4%) and 206 women (44.7%) were tested at the age of 50 years, and 309 men and 245 women were tested 10 years later. The subjects in the second part of the study came from the same original sample. At 70 years of age 171 men and 154 women and at 80 years of age 70 men and 68 women took part in the maximal test. RESULTS: The submaximal test results between the ages of 50 and 60 years showed a mean annual decline in body mass adjusted maximal power in sustained work (W/kg) of 0.54% in men and of 0.90% in women. Between the ages of 70 and 80 years, when the indirect maximal tests were applied, the annual decline in men was on average 1.79% and in women 3.03%. When the associations of submaximal test results at ages 50-60 years and the voluntary maximal test results at the higher ages were analyzed, a moderate positive correlation was observed with the results obtained at the age of 70 years. The survival analyses showed that the submaximal bicycle test results (W/kg body mass) at the age of 60 years had a predictive value for survival in women during the subsequent 10-year period. The same was true for the maximal test results obtained at the age of 70 years in men; a significantly larger proportion of men in the lowest quintile died during the subsequent 10 years than of those belonging to the higher quintiles. CONCLUSIONS: The changes in body mass related maximal power in sustained work observed in this population on the basis of longitudinal studies among the age groups 50-60 and 70-80 years indicated a steeper decline at the higher ages. The decline was relatively more pronounced in women than in men. However, differences in the test protocols employed at different times limit the possibilities for overall comparisons across the data. The results of the submaximal bicycle ergometer tests in middle-aged female subjects (60 years old) had a predictive value for survival over the 10 years immediately following the test; likewise, the voluntary maximal test results at higher ages predicted survival in men.

Age Distribution↗
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Nutritional status and associated factors on geriatric admission.

INTRODUCTION: The proportion of elderly patients who are undernourished is high and undernutrition has serious health implications. No consensus exists regarding nutritional screening measurements suitable for elderly patients. There is a need to identify risk factors for undernutrition in elderly patients to enable prevention and treatment. AIM: To identify clinically identifiable risk factors for undernutrition in geriatric patients on admission. METHODS: Newly admitted patients (n=196, mean age 83.7 years) were examined for nutritional risk factors by the nursing staff. Analyses of variance and multiple regression analyses were used to identify risk factors for undernutrition. RESULTS: Undernutrition was present in 41% of the patients using a Body Mass Index cut-off < 22 (kg/m2) as definition of undernutrition. Poor appetite, oral cavity problems, constipation and nausea or vomiting were frequent problems; the patients also used a high number of medical preparations, including preparations that induced nausea. No help with cooking before admission, poor appetite, oral cavity problems and high age were all significantly associated with undernutrition. CONCLUSION: To improve nursing care and to prevent undernutrition, it is recommended to routinely examine the patient's mouth and teeth on admission and to assess patients not only for their physical condition (appetite, oral health and nutritional status), but also for their living conditions e.g. help with cooking.

Aged, 80 and over↗