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Biomedical subjects

M Schmuziger

Publications and source records attributed to M Schmuziger.

17 recordsLinked to original sources

[Alternative closure of the sternum after heart surgery].

We report on 27 patients who, between November 1986 and December 1988, had a delayed sternal closure after cardiac surgery out of the following reasons: post-ECC low output syndrome: 17 patients (15 with IABP, 11 transfemoral, 4 transaortic), haemodynamic breakdown with sternal approximation: 9 patients, diffuse bleeding: one patient. In 13 patients perioperative infarction was diagnosed (4 right heart infarctions) as a cause for the poor cardiac condition. The surgery performed had been: 26 coronary artery bypass operations (18 combined with other procedures), and one double valve replacement. The temporary closure of the wound generally is now performed by a sterile zipper (Ethizip). Sternal closure was possible one to nineteen days postoperatively, most often (19 patients) on the 2nd postoperative day. We did not note any serious complications or wound infection due to the management with delayed sternal closure. Three patients died from cardiac failure with chest open, 4 patients died six days to eight weeks postoperatively with closed chest. Among the 20 patients discharged from hospital, 17 are at present in satisfactory clinical condition, one patient suffers from recurrent angina, one from cardiac insufficiency and one is in poor general condition. As a conclusion we think that delayed sternal closure after cardiac surgery is a helpful tool in patients with 1) haemodynamic breakdown with sternal approximation, 2) diffuse bleeding.

Coronary Artery Bypass

[Anti-infection prophylaxis in cardiac surgery: comparison of single-dose ceftriaxone and cefamandole in repeat doses].

The efficiency of a single two gram bolus of Ceftriaxone for cardiac operations was evaluated versus a classical, multiple dose, antibiotic prophylaxis using Cefamandole. The results were quite similar in both groups, with a very low infection rate. We conclude that a single bolus prophylaxis using a broad spectrum antibiotic is as efficient as an ordinary, multiple dose technique.

Aged

[Which factors determine early occlusion of aortocoronary venous transplants? An intraoperative analysis of surgical parameters].

From 1978 to 1982 1 364 patients received an aorto-coronary vein graft, reoperations not included. Immediately after the operation the surgeon had to document the intraoperatively taken findings like diameter and quality of the coronary arteries, diameter and quality of the veins, quality of the aorta, bypass-flow according to a standardized protocol. 806 patients could be coronarographied 8 weeks after. The influence of intraoperative findings on the early occlusion of aorto-coronary vein grafts is discussed.

Coronary Artery Bypass

Surgical techniques.

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Coronary Artery Bypass

Hemodynamics at rest and during exercise in 222 patients with coronary heart disease before and after aorto-coronary bypass surgery.

In 222 patients with coronary heart disease hemodynamics at rest and during exercise were measured before and after aortocoronary bypass surgery. A total of 552 grafts were constructed, i.e. an average of 2.47 grafts per patient. Only 10.8% of the patients had a 1-vessel-disease, 59.2% had a 3-vessel-disease. 10.8% of the patients were provided with one graft, 49.7% got 3 or 4 grafts. In 92.8% of the patients the r. desc. ant. was significantly stenosed, and in 94.2% this vessel has been provided with a graft. Preoperatively only 7 patients had no angina pectoris during exercise (bicycle ergometer in supine position, each load lasting 6 min), postoperatively 154 patients have been completely free of angina pectoris. The preoperative angina pectoris-free exercise tolerance was 27.4 +/- 27.4 W (means +/- SD), postoperatively it was 76.5 +/- 33.8 W. The largest increase of exercise tolerance was observed in patients with a 3-vessel-disease (208%). Preoperatively only 10.1% had normal values of pulmonary wedge pressure and cardiac output at rest and during exercise, postooperatively 51.5%. The postoperative normalization of hemodynamics depends on the number of vessels involved (1-vessel-disease 86%, 3-vessel-disease 39.8% normalization) and on the status of the left ventricle (without a previous transmural myocardial infarction 68.4%; with a previous myocardial infarction 41.0%). The effects of revascularization on myocardial ischemia can be evaluated by measurements of pulmonary wedge pressure and cardiac output at rest and during exercise.

Angina Pectoris

[Function improvement in levography following aortocoronary bypass].

Actively contracting segments, preoperatively akinetic, were found in 8 of 63 patients, evaluated 6-12 months after aortocoronary surgery by coronary angiography. Ejection fraction was increased from 48.1% (S.D. 15.7) to 68.3% (S.D. 11.4). These patients are characterized by two simple clinical parameters: 1. All patients had angina pectoris at rest or at minimum exercise except for one; 2. preoperatively, there was a discrepancy between severe ventriculographic and discreet Ecg findings. These findings prove that myocardial function in coronary artery disease can be impaired at rest by ischemia, without clinical signs of coronary insufficiency, such as angina pectoris. Even severe impairment of left ventricular function is no contraindication for coronary artery surgery, if caused by reversible myocardial ischemia.

Adult

[Cardiac surgery].

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Cardiac Surgical Procedures