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Biomedical subjects

M Schattenkirchner

Publications and source records attributed to M Schattenkirchner.

At least 91 records · Page 5Linked to original sources
PubMed1983

[Arthropathy in idiopathic hemochromatosis].

In 22 of 35 patients (63%) with idiopathic hemochromatosis arthropathy could be demonstrated. In 20 patients the metacarpophalangeal joints (mainly II and III) with preference of the right hand were affected. Chondrocalcinosis of the wrist and knee was found both in two patients with metacarpophalangeal joint disease and in two patients without metacarpophalangeal disease. Further joints affected were the wrists (14), the other finger joints (11), and the knees (6). The dominant clinical complaint was pain in motion. Swelling and redness were rare findings only in case of acute exacerbations. The radiologic changes in the metacarpophalangeal joints were narrowing of the joint spaces, subchondral cysts, sclerosis of subchondral bone of metacarpal heads, and marginal osteophytic appositions at the joints. In one third of the patients arthropathy was evident before the diagnosis of idiopathic hemochromatosis was made. Histocompatibility testing confirmed that HLA-A3 is significantly more frequent in patients with idiopathic hemochromatosis than in normal persons. A statistically significant difference concerning HLA-phenotypes between patients with arthropathy and patients without arthropathy could not be detected. There was no case of arthropathy when 98 relatives of the patients were examined. However, idiopathic hemochromatosis was first detected in ten persons of this group.

Chondrocalcinosis↗
PubMed1983

[Rheumatology].

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Germany, West↗
PubMed1982

[Eosinophilic fasciitis (Shulman syndrome)].

Scleroderma like skin indurations without internal organ involvement, joint contractures, eosinophilia, and inflammatory infiltration of the fascia between subcutis and muscle are considered as characteristic features of eosinophilic fasciitis (EF). We report a further case of a 30 years old diabetic confirming to the syndrome defined by Shulman 1974. Corticosteroid therapy resulted in remission of disease symptoms, however a rebiopsy revealed no effect of therapy on histopathologic changes. A critical review of 118 cases in the literature is presented to explore the relationship of EF to scleroderma.

Adrenal Cortex Hormones↗
PubMed1981

[Joint diseases as the early clinical symptom of hemochromatosis].

In three patients arthropathy was the earliest symptom of hemochromatosis. Two of these patients had a precirrhotic stage of hemochromatosis. The liver histology of the third patient showed a beginning cirrhosis. The serum iron ranged from 212 to 260 micrograms/dl. The transferrin saturation was 95-100%. Serum iron and transferrin should be determined in all patients with arthralgias, since arthropathy may be the first clinical sign of hemochromatosis.

Diagnosis, Differential↗
PubMed1981

[Xeroradiography and conventional radiological methods in chronic polyarthritis (author's transl)].

Xeroradiograms and conventional radiographs of the hands of 50 patients with chronic polyarthritis were performed. These were compared with regard to the features which are found in chronic polyarthritis. There were no significant differences between xeroradiography and conventional radiology. Xeroradiography was a little better for demonstrating changes in the soft tissues and erosions, but conventional radiographs were superior in showing osteoporosis, cysts and the absorption of subchondral lamellae. In general, xeroradiography and conventional procedures were of equal value in the diagnosis of chronic polyarthritis. For practical purposes, conventional radiography is to be preferred and xeroradiography may be regarded as an additional procedure, particularly for the investigation of soft tissue changes.

Adult↗
PubMed1980

[B27-positive diseases. A new concept in rheumatology (author's transl)].

In a large number of rheumatoid factor-negative arthritic conditions there is a number of diseases which are characterized by common clinical manifestations and the genetic property of the presence of B27. The term "B27-positive diseases" is based on a concept arising from intensive nosological studies and provides important suggestions for the study of the pathogenesis of a group of rheumatic diseases in that it emphasizes the significance of a genetic predisposition and makes an infectious etiology probable.

Arthritis↗
PubMed1977

[Echography of knee joint cysts (author's transl)].

Because of a palpable swelling, 57 popliteal fossae were examined echographically. In 24 cases, the echography revealed a probable Baker's cyst. This diagnosis was confirmed by arthrography or at operation in 21 of the 24 cases. Two of the three findings which did not correspond were due to over-interpretation of the echographic picture and can be avoided in future by giving particular intention to the sound intensity. The causes of the discrepancy in the third case are still undetermined. These results show that echography is suitable for the discovery and assessment of Baker's cysts and should be used first as a non-invasive, painless, rapidly reproducible method.

Diagnostic Errors↗