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Biomedical subjects

M Schaldach

Publications and source records attributed to M Schaldach.

At least 127 records · Page 7Linked to original sources

Electrochemistry of after-pacing potentials on electrodes.

Predictable electrochemical behavior of electrodes in physiologic pacemakers is desirable. The after-pacing potentials play a major role in determining precise sensing and pacing performance between both chambers. Ideally, pacemaker input impedance should be high (in relation to the electrode/blood interface), whereas the potential remaining on the electrode should be as low as possible. Both of these conditions are influenced by the electrode material, structure, and design. Results of in vivo and in vitro testing show that the after-pacing potential interference is directly related to the potential decay, and these values are in general considerably shorter than the blanking periods.

Electrochemistry↗

[A simple and reliable atrial pacemaker electrode: technique of transvenous implantation and clinical results with a metal hook electrode (author's transl)].

At present only about 1% of all implanted pacemakers are atrial triggered ones, although an indication for them exists in about 77% of cases. This disproportion is due to an overestimate of the difficulties encountered in fixing the electrode. The electrode developed by Irnich has now been modified to provide good fixation for atrial stimulation, as well as recording of atrial potentials. Preliminary results in 20 patients have been favourable. Over a seven-month observation period there have been no instances of dislocation or loss of effective stimulation.

Electrocardiography↗

A multichannel telemetry system for long-term in vivo evaluation of implantable materials.

Long-term in vivo measurements of the corrosion potentials of various implantable metal materials are performed using an implantable multichannel telemetry system. The data acquisition system has been designed to achieve maximum ease of operation for routine tests in animal applications. A novel signal encoding technique offers advantageous properties in connection with a commercial audio cassette tape recorder for signal storage. The flexibility of the design extends the scope of application to include not only biomaterial testing but all low frequency data transmissions in biological research.

Animals↗

[Implantable materials (author's transl)].

There is a steadily increasing importance of implants used as substitutions for body functions which have been impaired due to disease, natural abrasion or accident. With the present state of the art, the limitations for the application of surgical substitutions are due to insufficient properties of biomaterials with regard to specific applications as well as to deficiencies in design and function of the implants used. The basis for the improvement and new development of implants is therefore a functionally adequate design in which the specific properties of the material are taken into account with regard to the individual requirements of the implantation site. For orthopedic implants, materials have to be developed which are to a large extent corrosion and degradation resistant, and withstand high mechanical stress. For implants in the cardiovascular system, compatibility with blood is most significant. Present research in this field is concentrated on efforts to improve the thromboresistivity of conventional polymers by different kinds of surface treatments. One possibility is to influence actively the electrochemical interactions between material and blood components, e.g. by the use of redox catalysts.

Animals↗