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Biomedical subjects

M Schaapveld

Publications and source records attributed to M Schaapveld.

3 recordsLinked to original sources

Relationship of tumor thickness in punch biopsy and subsequent surgical specimens in stage I squamous cell carcinoma of the lower lip.

OBJECTIVE: Among the histologic features of squamous cell carcinoma of the lower lip, maximum tumor thickness in particular is a predictor of regional nodal metastatic spread and thus an important parameter in treatment planning. The purpose of this study was to investigate the relationship between maximum tumor thickness in punch biopsies and maximum tumor thickness in subsequent surgical specimens. STUDY DESIGN: This retrospective study examined the relationship between maximum tumor thickness in punch biopsies with that in subsequent surgical specimens obtained in 72 patients with clinical stage I squamous cell carcinoma of the lower lip. RESULTS: A correlation between maximum tumor thickness in punch biopies and in subsequent surgical specimens was found only for tumors with a thickness less than 3 mm. CONCLUSIONS: Reliable predictive information could be obtained from punch biopsies with a maximum tumor thickness less than 3 mm. When the maximum tumor thickness exceeds 3 mm, better information may be obtained from either a large incisional biopsy or the surgical specimen.

Adult

Epidemiology of cancer of the lip in The Netherlands.

Descriptive epidemiological data of new cases of squamous cell carcinoma of the vermilion border of the lip in the Netherlands from 1989-94 inclusive are presented. Lip cancer represented 0.47 and 0.09% of all new malignancies in males and females, respectively. The lower lip was the most frequently affected site. The majority of the lip cancers were diagnosed in tumour stage I. The median age at diagnosis in males was 68 years, 5 years less than in females. The overall male-to-female ratio was 5.7. Age-adjusted incidence rates in males and females were 2.2 and 0.3 per 100,000 (ESR), respectively. The cumulative lifetime risk for developing lip cancer was 0.15 for males and 0.03 for females. Mortality/incidence ratios in males and females were 0.05 and 0.07, respectively. Differences in lip cancer incidence were observed between an urban and a rural area. There was a positive association between the occurrence of lip cancer and rural residence; rate ratios were 3.3 among males and 3.5 among females.

Adolescent

Increasing on-task behaviour through interruption-prompting.

This study was designed to assess the effects of response-contingent interruption-prompting of stereotypic behaviour on on-task behaviour, inactivity and inappropriate behaviour. Also, the relationship between these behaviours was investigated. Five individuals with severe intellectual disability and autism participated. Data were collected within a reversal design. The results showed a statistically significant increase of on-task behaviour when interruption-prompting of stereotypic behaviour was in effect. Inactivity was statistically related to inappropriate behaviour. In terms of the continuous effort to identify procedures that are least intrusive for the client to attain behaviour improvement, it is suggested that interruption-prompting of stereotypic behaviour may be a reasonable choice for practicians.

Adolescent